Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 11/20 | 0.70 |
| ▸ | RXRB | P28702 | 8/20 | 0.70 |
| ▸ | RARB | P10826 | 12/20 | 0.46 |
| ▸ | RARG | P13631 | 12/20 | 0.46 |
| ▸ | RARA | P10276 | 8/20 | 0.46 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 6/20 | 0.41 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7422602 | 0.83 | RXRA (1.00) | RXRARXRBRARBRARGRARA | |
| SCHEMBL7760189 | 0.82 | RXRA (0.78) | RXRARXRBRARBRARGRARA | |
| SCHEMBL7759700 | 0.82 | RXRA (0.53) | RXRARXRBRARBRARGRARA | |
| SCHEMBL8557387 | 0.81 | RXRA (0.49) | RXRARXRBRARBRARGRARA | |
| SCHEMBL3175854 | 0.80 | RXRA (0.57) | RXRARXRBRARBRARGRARA | |
| SCHEMBL7762896 | 0.79 | RXRA (0.65) | RXRARXRBRARBRARGRARA | |
| SCHEMBL8736104 | 0.79 | RXRA (0.50) | RXRARXRBRARBRARGRARA | |
| SCHEMBL7756674 | 0.79 | RXRA (0.50) | RXRARXRBRARBRARGRARA | |
| SCHEMBL8681351 | 0.78 | RXRA (0.56) | RXRARXRBRARBRARGRARA | |
| Bromide SCHEMBL9157069 | 0.78 | RXRA (0.49) | RXRARXRBRARBRARGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915823-B1 | BI-AROMATIC COMPOUNDS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME AND USES | CT INTERNAT DE (FR) | 2001-04-18 | — | — | EP | claimed |
| EP-0915823-B1 | BI-AROMATIC COMPOUNDS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME AND USES | CT INTERNAT DE (FR) | 2001-04-18 | — | — | EP | disclosed |