Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 2/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.40 |
| ▸ | NPR3 | P17342 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4835676 | 0.87 | CTSK (0.45) | CTSSCTSKITGA4ITGB7PRSS1 | |
| SCHEMBL10441697 | 0.86 | KMT2A (0.47) | PRSS1CTSGCTRB1CMA1ANPEP | |
| SCHEMBL7061908 | 0.78 | CTSK (0.50) | CTSSCTSKITGA4ITGB7PRSS1 | |
| SCHEMBL13570858 | 0.77 | LTA4H (0.51) | MEN1KMT2A | |
| SCHEMBL487448 | 0.77 | CTSK (0.49) | CTSSCTSKITGA4ITGB7PRSS1 | |
| SCHEMBL487446 | 0.77 | CTSK (0.49) | CTSSCTSKITGA4ITGB7PRSS1 | |
| SCHEMBL12221989 | 0.76 | CTSK (0.48) | CTSSCTSKITGA4ITGB7PRSS1 | |
| SCHEMBL2307679 | 0.76 | LTA4H (0.55) | CTSSCTSKITGA4ITGB7MMP1 | |
| SCHEMBL27878054 | 0.76 | LTA4H (0.55) | CTSSCTSKITGA4ITGB7MMP1 | |
| SCHEMBL2307682 | 0.76 | LTA4H (0.55) | CTSSCTSKITGA4ITGB7MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5783573-A | Pharmaceuticals which promote gastrointestinal blood circulation | SOLVAY PHARMACEUTICALS GMBH (DE) | 1998-07-21 | — | — | US | disclosed |
| US-5677297-A | ENZYME INHIBITOR FOR TREATING THE HEART FAILURE TO REDUCE THE CARDIAC PRESSURE, DIURETICS | SOLVAY PHARMACEUTICALS GMBH (DE) | 1997-10-14 | — | — | US | disclosed |