Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.59 |
| ▸ | LTA4H | P09960 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 2/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22692744 | 0.94 | KCNA3 (0.56) | KCNA3LTA4HTDP1HDAC3HDAC4 | |
| SCHEMBL11583149 | 0.89 | KCNA3 (0.52) | KCNA3LTA4HTDP1HTR1BCHRNB2 | |
| SCHEMBL9812236 | 0.86 | RAB9A (0.54) | HDAC6CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL9812241 | 0.86 | RAB9A (0.54) | HDAC6CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL6547805 | 0.86 | LTA4H (0.64) | KCNA3LTA4HHDAC3HDAC4HDAC1 | |
| SCHEMBL28592582 | 0.86 | LTA4H (0.64) | KCNA3LTA4HHDAC3HDAC4HDAC1 | |
| SCHEMBL28601360 | 0.86 | KCNA3 (0.55) | KCNA3LTA4HTDP1HDAC3HDAC4 | |
| SCHEMBL28597217 | 0.86 | LTA4H (0.64) | KCNA3LTA4HHDAC3HDAC4HDAC1 | |
| SCHEMBL28599930 | 0.86 | LTA4H (0.59) | KCNA3LTA4HTDP1HDAC3HDAC4 | |
| SCHEMBL28590811 | 0.86 | LTA4H (0.59) | KCNA3LTA4HTDP1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697387-B1 | Improved method for the preparation of iodonium salts | DOW CORNING (US) | 1998-04-22 | — | — | EP | claimed |
| EP-0697387-A2 | Improved method for the preparation of iodonium salts | DOW CORNING CORPORATION (US) | 1996-02-21 | — | — | EP | claimed |
| US-5426222-A | Mixing iodoarene dicarboxylate, solvent, adding acid to form homogeneous reaction mixture, reacting with benzene or substituted benzene, stripping solvent | DOW CORNING CORPORATION (US) | 1995-06-20 | — | — | US | claimed |
| EP-0697387-B1 | Improved method for the preparation of iodonium salts | DOW CORNING (US) | 1998-04-22 | — | — | EP | disclosed |
| EP-0697387-A2 | Improved method for the preparation of iodonium salts | DOW CORNING CORPORATION (US) | 1996-02-21 | — | — | EP | disclosed |
| US-5426222-A | Mixing iodoarene dicarboxylate, solvent, adding acid to form homogeneous reaction mixture, reacting with benzene or substituted benzene, stripping solvent | DOW CORNING CORPORATION (US) | 1995-06-20 | — | — | US | disclosed |