SCHEMBL27908528

SCHEMBL27908528

CCO[Si](OCC)(OCC)C(C)(C(=O)O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.42
HIF1A Q16665 1/20 0.42
CHRM2 P08172 5/20 0.41
CHRM4 P08173 4/20 0.41
CHRM1 P11229 4/20 0.41
CHRM3 P20309 4/20 0.41
CHRM5 P08912 2/20 0.41
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41
KMT2A Q03164 2/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27891666 0.80 KCNN4 (0.46) CYP2C19HIF1ACHRM2CHRM4CHRM1
SCHEMBL8736449 0.80 MAPK1 (0.41) CYP2C19HIF1ACHRM2CHRM4CHRM1
SCHEMBL4275809 0.78 KMT2A (0.40) KMT2AMAPTPOLBALDH1A1MEN1
SCHEMBL240934 0.77 PPARA (0.46) HDAC1KMT2AMAPTALDH1A1MEN1
SCHEMBL6130465 0.77 PPARA (0.45) KMT2AMAPTALDH1A1MEN1CYP1A2
SCHEMBL27908532 0.77 CYP2C19 (0.46) CYP2C19HIF1ACHRM2CHRM4CHRM1
SCHEMBL6512003 0.76 MAPK1 (0.41) CYP2C19HIF1ACHRM2CHRM4CHRM1
SCHEMBL17968317 0.76 CYP2C19 (0.42) CYP2C19HIF1ACHRM2CHRM4CHRM1
SCHEMBL9716560 0.74 MAPK1 (0.43) CYP2C19HIF1ACHRM2CHRM4CHRM1
SCHEMBL6332001 0.74 KCNN4 (0.39) CHRM2CHRM4CHRM1CHRM3CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103172655-A Organosiloxane containing acid anhydride group and method for preparing the same SHINETSU CHEMICAL CO 2013-06-26 CN disclosed
CN-103131011-A Organosiloxane containing anhydride groups and manufacturing method thereof SHINETSU CHEMICAL CO 2013-06-05 CN disclosed
CN-102942585-A Succinic anhydride group containing cyclic organosiloxane, preparation thereof, organosiloxane composition and thermosetting resin composition SHINETSU CHEMICAL CO 2013-02-27 CN disclosed