SCHEMBL9716560

SCHEMBL9716560

CCO[Si](OCC)(C(C)(C)c1ccccc1)C(C)(C)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.43
ALDH1A1 P00352 2/20 0.40
TAAR1 Q96RJ0 1/20 0.40
ALOX15 P16050 1/20 0.40
KCNN4 O15554 2/20 0.39
LTA4H P09960 1/20 0.38
CYP2C19 P33261 2/20 0.36
HIF1A Q16665 1/20 0.36
MEN1 O00255 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
NPY2R P49146 1/20 0.36
KMT2A Q03164 1/20 0.36
ESR1 P03372 2/20 0.34
ESR2 Q92731 2/20 0.34
CYP3A4 P08684 1/20 0.34
POLB P06746 1/20 0.34
NR3C2 P08235 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8736449 0.85 MAPK1 (0.41) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL9716571 0.83 MAPK1 (0.40) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL29022732 0.83 MAPK1 (0.40) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL10627099 0.80 MAPK1 (0.38) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL10628347 0.80 MAPK1 (0.38) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL20658045 0.80 KCNN4 (0.40) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL6512003 0.77 MAPK1 (0.41) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL19816724 0.75 LTA4H (0.39) ALDH1A1LTA4H
SCHEMBL7638116 0.75 MAPK1 (0.48) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL6332001 0.74 KCNN4 (0.39) MAPK1ALDH1A1TAAR1ALOX15KCNN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108473684-B Process for producing siloxane polymer 东丽精细化工株式会社 2023-05-12 CN disclosed
EP-0282341-B1 PROCESS FOR POLYMERIZATION OF OLEFINS AND POLYMERIZATION CATALYST MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-05-20 EP disclosed
EP-0455313-A1 Process for polymerization of olefins and polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-11-06 EP disclosed
US-5028671-A Using coordination catalyst contining magnesium, titanium, halogen compounds with organoaluminum and organosilicon compounds MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-07-02 US disclosed
EP-0282341-A1 Process for polymerization of olefins and polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-09-14 EP disclosed