SCHEMBL8736478

SCHEMBL8736478

CN(C)C1CC(=O)NC1=O

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAP3K14 Q99558 1/20 0.44
CRBN Q96SW2 14/20 0.42
DDB1 Q16531 13/20 0.41
CYP19A1 P11511 1/20 0.34
GAA P10253 1/20 0.33
TSHR P16473 1/20 0.33
NPC1 O15118 1/20 0.32
IDO1 P14902 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13257399 0.77 DDB1 (0.57) CRBNDDB1
SCHEMBL23267307 0.77 DDB1 (0.57) CRBNDDB1
SCHEMBL27972081 0.71 CRBN (0.39) MAP3K14CRBNDDB1
SCHEMBL26620907 0.71 CRBN (0.43) MAP3K14CRBNDDB1CYP19A1GAA
SCHEMBL19359375 0.69 DDB1 (0.74) CRBNDDB1TSHR
SCHEMBL26620898 0.68 CRBN (0.31) CRBNDDB1
SCHEMBL10587757 0.68 ALDH1A1 (0.42) MAP3K14CRBNDDB1NPC1
SCHEMBL10575481 0.67 MAP3K14 (0.36) MAP3K14CRBNDDB1CYP19A1GAA
SCHEMBL10053017 0.67
SCHEMBL14387952 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150024984-A1 FRICTION MODIFIERS FOR ENGINE OILS AFTON CHEMICAL CORPORATION 2015-01-22 US disclosed
EP-2826841-A1 Friction modifiers for engine oils Afton Chemical Corporation (US) 2015-01-21 EP disclosed
CN-104293417-A Friction modifiers for engine oils AFTON CHEMICAL CORP 2015-01-21 CN disclosed
US-8927471-B1 Friction modifiers for engine oils AFTON CHEMICAL CORPORATION (US) 2015-01-06 US disclosed
EP-0598404-B1 Plant growth regulator composition KUMIAI CHEMICAL INDUSTRY CO (JP) 1998-08-05 EP disclosed
US-5510321-A ADJUVANTS COMPRISE NITROGEN CONTAINING WATER SOLUBLE INORGANIC COMPOUNDS OR UREA KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1996-04-23 US disclosed
US-5436225-A Of a cyclohexane compound, a water soluble nitrogen compound and an etherified polyether, mineral oil or vegetable oil KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1995-07-25 US disclosed
EP-0598404-A1 Plant growth regulator composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1994-05-25 EP disclosed