Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | PAM | P19021 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8736683 | 1.00 | IDO1 (0.48) | IDO1HTR2APAMMAOBSIGMAR1 | |
| SCHEMBL2658016 | 0.78 | ALDH1A1 (0.39) | IDO1HTR2AMAOBMAOACYP19A1 | |
| SCHEMBL28643001 | 0.78 | CYP1A2 (0.47) | IDO1HTR2APAMSIGMAR1 | |
| SCHEMBL28491229 | 0.78 | IDO1 (0.42) | IDO1HTR2APAMMAOBSIGMAR1 | |
| SCHEMBL1002069 | 0.76 | MAOB (0.49) | IDO1HTR2APAMMAOBSIGMAR1 | |
| SCHEMBL3012608 | 0.76 | MAOB (0.49) | IDO1HTR2APAMMAOBSIGMAR1 | |
| SCHEMBL5347513 | 0.74 | IDO1 (0.47) | IDO1HTR2APAMMAOBSIGMAR1 | |
| SCHEMBL95861 | 0.74 | PAM (0.52) | IDO1HTR2APAMMAOB | |
| SCHEMBL95862 | 0.74 | PAM (0.52) | IDO1HTR2APAMMAOB | |
| SCHEMBL4863423 | 0.71 | IDO1 (0.58) | IDO1HTR2APAMMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540259-B1 | Integrated thermoplastic resin/silicone rubber articles and methods of making them | SHINETSU CHEMICAL CO (JP) | 1998-03-11 | — | — | EP | claimed |