SCHEMBL8736879

SCHEMBL8736879

O=S(=O)(NS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)S(=O)(=O)N1CCC(N2CCCC2)CC1)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.36
GAA P10253 2/20 0.36
ALDH1A1 P00352 3/20 0.35
L3MBTL1 Q9Y468 2/20 0.34
EBP Q15125 1/20 0.34
DHCR7 Q9UBM7 1/20 0.34
OGFRL1 Q5TC84 1/20 0.34
NPC1 O15118 1/20 0.33
MBTD1 Q05BQ5 2/20 0.33
L3MBTL3 Q96JM7 2/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
HPGD P15428 1/20 0.32
USP5 P45974 2/20 0.31
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL178329 0.99 KDM4E (0.38) KDM4EGAAALDH1A1L3MBTL1EBP
SCHEMBL10087742 0.85 CA1 (0.33) KMT2A
SCHEMBL12465140 0.82 MEN1 (0.36) KDM4EMEN1KMT2A
SCHEMBL14682255 0.81 CA1 (0.37) KDM4EALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL8736915 0.80 KDM4E (0.40) KDM4EGAAALDH1A1L3MBTL1EBP
SCHEMBL13008891 0.79 KDM4E (0.41) KDM4EGAAALDH1A1L3MBTL1EBP
SCHEMBL16661697 0.78 CNR2 (0.31)
SCHEMBL13127923 0.78
SCHEMBL15203374 0.77 KDM4E (0.43) KDM4EGAAALDH1A1L3MBTL1EBP
SCHEMBL13464444 0.76 CA1 (0.35) KDM4EALDH1A1L3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120129100-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, AND RESIST FILM AND PATTERN FORMING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2012-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120129100-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, AND RESIST FILM AND PATTERN FORMING METHOD USING THE SAME ACTR8, RAD51, ACTR2 KDM4E 2980/4885GAA 1364/4885ALDH1A1 2640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.