⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27975846 | 0.98 | — | — | |
| SCHEMBL27873946 | 0.79 | — | — | |
| SCHEMBL27515498 | 0.79 | ALDH1A1 (0.40) | — | |
| SCHEMBL29166066 | 0.72 | — | — | |
| SCHEMBL5266610 | 0.72 | — | — | |
| SCHEMBL28212009 | 0.69 | NAMPT (0.38) | — | |
| SCHEMBL29881807 | 0.68 | NAMPT (0.47) | — | |
| SCHEMBL27279585 | 0.68 | ESR1 (0.35) | — | |
| Trifluoroacetic Acid SCHEMBL31460049 | 0.67 | HRH4 (0.49) | — | |
| SCHEMBL31754267 | 0.67 | NAMPT (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118639282-B | Tin spraying solution, preparation method thereof and application of tin spraying solution in spraying process | 昆山一鼎工业科技有限公司 | 2024-11-26 | — | — | CN | claimed |
| CN-118639282-A | Tin spraying solution, preparation method thereof and application of tin spraying solution in spraying process | 昆山一鼎工业科技有限公司 | 2024-09-13 | — | — | CN | claimed |
| CN-104203929-A | A new process for preparation of 4-methyloxazole-5-carboxylic ester | DSM IP ASSETS BV | 2014-12-10 | — | — | CN | claimed |
| CN-102453028-B | Antifungal agent-2- [ (2, 3-dihydro-4H-benzo [ b ] thiopyran-4-ylidene) hydrazono ] -4-oxotetrahydrothia (oxazole) -5-acetic acid derivative | UNIV SHENYANG PHARMACEUTICAL | 2014-07-30 | — | — | CN | claimed |
| CN-102453028-A | Antifungal agent-2- [ (2, 3-dihydro-4H-benzo [ b ] thiopyran-4-ylidene) hydrazono ] -4-oxotetrahydrothia (oxazole) -5-acetic acid derivative | UNIV SHENYANG PHARMACEUTICAL | 2012-05-16 | — | — | CN | claimed |
| US-20250368614-A1 | COMPOUNDS AND METHODS FOR YAP/TEAD MODULATION AND INDICATIONS THEREFOR | Opna Bio SA (CH) | 2025-12-04 | — | — | US | disclosed |
| EP-4654969-A1 | COMPOUNDS AND METHODS FOR YAP/TEAD MODULATION AND INDICATIONS THEREFOR | Opna Bio SA (CH) | 2025-12-03 | — | — | EP | disclosed |
| US-20250188075-A1 | SUBSTITUTED HETEROCYCLIC CSNK1 INHIBITORS | THE BROAD INSTITUTE, INC. | 2025-06-12 | — | — | US | disclosed |
| EP-4469457-A1 | SUBSTITUTED HETEROCYCLIC CSNK1 INHIBITORS | The Broad Institute Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| CN-118639282-B | Tin spraying solution, preparation method thereof and application of tin spraying solution in spraying process | 昆山一鼎工业科技有限公司 | 2024-11-26 | — | — | CN | disclosed |
| CN-118639282-A | Tin spraying solution, preparation method thereof and application of tin spraying solution in spraying process | 昆山一鼎工业科技有限公司 | 2024-09-13 | — | — | CN | disclosed |
| US-20240279215-A1 | NAMPT MODULATORS | CYTOKINETICS, INCORPORATED | 2024-08-22 | — | — | US | disclosed |
| CN-102453028-A | Antifungal agent-2- [ (2, 3-dihydro-4H-benzo [ b ] thiopyran-4-ylidene) hydrazono ] -4-oxotetrahydrothia (oxazole) -5-acetic acid derivative | UNIV SHENYANG PHARMACEUTICAL | 2012-05-16 | — | — | CN | disclosed |
| CN-102453028-A | Antifungal agent-2- [ (2, 3-dihydro-4H-benzo [ b ] thiopyran-4-ylidene) hydrazono ] -4-oxotetrahydrothia (oxazole) -5-acetic acid derivative | UNIV SHENYANG PHARMACEUTICAL | 2012-05-16 | — | — | CN | disclosed |
| WO-2012040258-A2 | THERAPEUTIC PIPERAZINES | HELICON THERAPEUTICS, INC. (US) | 2012-03-29 | — | — | WO | disclosed |
| US-20110065691-A1 | THERAPEUTIC PIPERAZINES | DART NEUROSCIENCE (CAYMAN) LTD. (KY) | 2011-03-17 | — | — | US | disclosed |
| CN-101282972-A | Piperidine and piperazine derivatives as P2X3 antagonists | HOFFMANN LA ROCHE (CH) | 2008-10-08 | — | — | CN | disclosed |
| US-6242448-B1 | Trisubstituted-oxazole derivatives as serotonin ligands | AMERICAN HOME PRODUCTS CORPORATION | 2001-06-05 | — | — | US | disclosed |
| US-4203896-A | WITH MERCURIC ACETATE AND ACETIC ACID, ACIDIC HYDROLYSIS OF N-PROPENYL GROUP | ELI LILLY AND COMPANY (US) | 1980-05-20 | — | — | US | disclosed |
| US-4144232-A | Substituted azetidin-2-one antibiotics | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |