Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.49 |
| ▸ | NCF1 | P14598 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29723103 | 1.00 | CNR2 (0.49) | CNR2NCF1CYP1A2NOS2BACE1 | |
| Hydrochloric Acid SCHEMBL4591179 | 0.98 | CNR2 (0.47) | CNR2NCF1CYP1A2NOS2BACE1 | |
| Hydrochloric Acid SCHEMBL16825201 | 0.98 | CNR2 (0.47) | CNR2NCF1CYP1A2NOS2BACE1 | |
| Quinoline SCHEMBL28188354 | 0.89 | ALDH1A1 (0.61) | CNR2NCF1CYP1A2NOS2BACE1 | |
| SCHEMBL29076986 | 0.83 | CNR2 (0.48) | CNR2ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL24716272 | 0.83 | NCF1 (0.48) | CNR2NCF1CYP1A2NOS2BACE1 | |
| SCHEMBL537850 | 0.83 | NCF1 (0.43) | CNR2NCF1CYP1A2NOS2BACE1 | |
| SCHEMBL28459107 | 0.83 | NCF1 (0.43) | CNR2NCF1CYP1A2NOS2BACE1 | |
| SCHEMBL15346405 | 0.81 | MAPT (0.48) | CNR2NCF1CYP1A2NOS2BACE1 | |
| SCHEMBL6543474 | 0.79 | NCF1 (0.48) | NCF1CYP1A2NOS2BACE1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 374 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947404-B | Concrete for mountain gas tunnel and preparation method thereof | 湖南中大设计院有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-116947404-A | Concrete for mountain gas tunnel and preparation method thereof | 湖南中大设计院有限公司 | 2023-10-27 | — | — | CN | claimed |
| CN-116887609-A | Perovskite thin film layer and preparation method thereof, perovskite silicon laminated solar cell and preparation method thereof | 通威太阳能（成都）有限公司 | 2023-10-13 | — | — | CN | claimed |
| CN-116178254-B | Method for preparing 2-trifluoromethyl quinoline | 南通大学 | 2023-10-03 | — | — | CN | claimed |
| CN-116840316-A | Preparation method of moisture-resistant formaldehyde sensor material and device application thereof | 华南师范大学 | 2023-10-03 | — | — | CN | claimed |
| CN-115466212-B | 2-trifluoromethyl quinoline compound and synthetic method and application thereof | 河南农业大学 | 2023-09-22 | — | — | CN | claimed |
| CN-114539702-B | Polymer material for looped network treatment control device and preparation method thereof | 浙江涌原新能科技股份有限公司 | 2023-08-11 | — | — | CN | claimed |
| CN-114231000-B | Environment-friendly flame-retardant weather-resistant ABS/PC composite material and preparation method thereof | 上海祺申塑业股份有限公司 | 2023-08-01 | — | — | CN | claimed |
| CN-116178254-A | Method for preparing 2-trifluoromethyl quinoline | 南通大学 | 2023-05-30 | — | — | CN | claimed |
| CN-115466212-A | 2-trifluoromethyl quinoline compound and synthetic method and application thereof | 河南农业大学 | 2022-12-13 | — | — | CN | claimed |
| CN-101646652-A | Quinoline derivatives and pharmaceutical compositions comprising them for selectin inhibition | WYETH CORP US | 2010-02-10 | — | — | CN | claimed |
| CN-101541751-A | Quinoline compounds | WYETH CORP (US) | 2009-09-23 | — | — | CN | claimed |
| EP-2074098-A2 | QUINOLINE COMPOUNDS | Wyeth (US) | 2009-07-01 | — | — | EP | claimed |
| WO-2009045382-A1 | SUBSTITUTED ARYL SULFONE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | MERCK & CO., INC. (US) | 2009-04-09 | — | — | WO | claimed |
| WO-2008049047-A2 | QUINOLINE COMPOUNDS | WYETH (US) | 2008-04-24 | — | — | WO | claimed |
| EP-1910334-A2 | COMPOUNDS AND METHODS FOR TREATMENT OF AMYLOID-BETA-PEPTIDE RELATED DISORDERS | Exonhit Therapeutics SA (FR) | 2008-04-16 | — | — | EP | claimed |
| WO-2007034329-A2 | COMPOUNDS AND METHODS FOR TREATMENT OF AMYLOID-BETA-PEPTIDE RELATED DISORDERS | EXONHIT THERAPEUTICS SA (FR) | 2007-03-29 | — | — | WO | claimed |
| WO-1998033786-A9 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | — | 1998-12-30 | — | — | WO | claimed |
| WO-1998033786-A1 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-08-06 | — | — | WO | claimed |
| CN-87105263-A | Polyhydroxylated and highly fluorinated compound and preparation method thereof and as the application of tensio-active agent | — | 1988-06-15 | — | — | CN | claimed |