Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 4/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9094342 | 0.87 | MDM2 (0.35) | CTRB1ATMLMNAALDH1A1GLA | |
| SCHEMBL7638594 | 0.81 | HIF1A (0.37) | ATMLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL8740392 | 0.81 | CTRB1 (0.38) | CTRB1MDM2NPC1RAB9APSMB5 | |
| SCHEMBL7563870 | 0.81 | PPARG (0.32) | LMNAALDH1A1PPARGPPARAPSMB5 | |
| SCHEMBL8818025 | 0.78 | TSHR (0.37) | LMNAALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL5798396 | 0.75 | — | — | |
| SCHEMBL7744301 | 0.75 | — | — | |
| SCHEMBL7744298 | 0.75 | — | — | |
| SCHEMBL8541705 | 0.75 | ADRB3 (0.36) | — | |
| SCHEMBL7743886 | 0.75 | ALDH1A1 (0.36) | ATMLMNAALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647139-A4 | ADHESIN-OLIGOSACCHARIDE CONJUGATE VACCINE FOR -i(HAEMOPHILUS INFLUENZAE). | MICROCARB INC (US) | 1997-09-03 | — | — | EP | disclosed |
| EP-0647139-A1 | ADHESIN-OLIGOSACCHARIDE CONJUGATE VACCINE FOR $i(HAEMOPHILUS INFLUENZAE) | MICROCARB, INC. (US) | 1995-04-12 | — | — | EP | disclosed |