Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 3/20 | 0.70 |
| ▸ | SCN2A | Q99250 | 6/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 5/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3057838 | 0.82 | PIN1 (1.00) | PIN1SCN2ANPY5RUSP30RECQL | |
| SCHEMBL25478641 | 0.79 | PIN1 (0.74) | PIN1SCN2ANPY5RUSP30RECQL | |
| SCHEMBL10242707 | 0.79 | PIN1 (0.74) | PIN1SCN2ANPY5RUSP30RECQL | |
| SCHEMBL23833724 | 0.79 | PIN1 (0.74) | PIN1SCN2ANPY5RUSP30RECQL | |
| SCHEMBL23832719 | 0.78 | PIN1 (0.72) | PIN1SCN2ANPY5RUSP30RECQL | |
| SCHEMBL25139612 | 0.75 | PIN1 (0.68) | PIN1SCN2ANPY5RUSP30RECQL | |
| SCHEMBL4416642 | 0.75 | PIN1 (0.68) | PIN1SCN2ANPY5RRECQLHPGDS | |
| SCHEMBL10927029 | 0.72 | SCN2A (0.61) | PIN1SCN2ANPY5RRECQLHPGDS | |
| SCHEMBL4081417 | 0.72 | PIN1 (0.62) | PIN1RECQLHPGDSCYP1A2MAPK1 | |
| SCHEMBL23833743 | 0.72 | PIN1 (0.62) | PIN1SCN2ANPY5RUSP30RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734398-A4 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 1997-04-16 | — | — | EP | disclosed |
| EP-0734398-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-10-02 | — | — | EP | disclosed |
| WO-1995016712-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-06-22 | — | — | WO | disclosed |