Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.74 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.52 |
| ▸ | NQO2 | P16083 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 3/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3057838 | 0.85 | PIN1 (1.00) | PIN1SCN2ANPY5RNQO2RECQL | |
| SCHEMBL14248239 | 0.83 | PIN1 (0.51) | PIN1NQO2PARP1CHEK2DHODH | |
| SCHEMBL10242707 | 0.82 | PIN1 (0.74) | PIN1SCN2ANPY5RNQO2RECQL | |
| SCHEMBL23833724 | 0.82 | PIN1 (0.74) | PIN1SCN2ANPY5RNQO2RECQL | |
| SCHEMBL23832719 | 0.81 | PIN1 (0.72) | PIN1SCN2ANPY5RNQO2RECQL | |
| SCHEMBL8740569 | 0.79 | PIN1 (0.70) | PIN1SCN2ANPY5RNQO2RECQL | |
| SCHEMBL25139612 | 0.78 | PIN1 (0.68) | PIN1SCN2ANPY5RNQO2RECQL | |
| SCHEMBL4416642 | 0.78 | PIN1 (0.68) | PIN1SCN2ANPY5RNQO2RECQL | |
| SCHEMBL11666314 | 0.78 | PIN1 (0.54) | PIN1SCN2ANPY5RNQO2PARP1 | |
| SCHEMBL8741207 | 0.75 | PIN1 (0.54) | PIN1SCN2ANPY5RNQO2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114315754-B | Hydroxamic acid compound and application thereof | 南方医科大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-114315754-B | Hydroxamic acid compound and application thereof | 南方医科大学 | 2023-06-06 | — | — | CN | disclosed |
| US-20230159509-A1 | PYRIDINESULFONAMIDE DERIVATIVES AS TRAP1 MODULATORS AND USES THEREOF | AMATHUS THERAPEUTICS, INC. (US) | 2023-05-25 | — | — | US | disclosed |
| US-20230159509-A1 | PYRIDINESULFONAMIDE DERIVATIVES AS TRAP1 MODULATORS AND USES THEREOF | AMATHUS THERAPEUTICS, INC. (US) | 2023-05-25 | — | — | US | disclosed |
| CN-114315754-A | Hydroxamic acid compound and application thereof | 南方医科大学 | 2022-04-12 | — | — | CN | disclosed |
| CN-114315754-A | Hydroxamic acid compound and application thereof | 南方医科大学 | 2022-04-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159509-A1 | PYRIDINESULFONAMIDE DERIVATIVES AS TRAP1 MODULATORS AND USES THEREOF | TRAP1, PINK1, PPM1D | PIN1 3297/4885SCN2A 1029/4885NPY5R 3043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.