Methyl Alcohol

Methyl Alcohol

SCHEMBL8740639

CC(=O)Nc1cccc(/C=C/C(=O)O)c1C.CO

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
HPGD P15428 1/20 0.45
CYP2C19 P33261 3/20 0.44
POLB P06746 3/20 0.44
CYP2C9 P11712 2/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
NFKB1 P19838 1/20 0.44
CA4 P22748 1/20 0.44
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
AKR1C3 P42330 1/20 0.42
AKR1C2 P52895 1/20 0.42
KDM4E B2RXH2 3/20 0.40
MAPT P10636 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
GAA P10253 1/20 0.40
LPAR2 Q9HBW0 1/20 0.40
LPAR3 Q9UBY5 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11110867 0.98 ALDH1A1 (0.46) ALDH1A1HPGDCYP2C19POLBCYP2C9
SCHEMBL11110869 0.98 ALDH1A1 (0.46) ALDH1A1HPGDCYP2C19POLBCYP2C9
Methyl Alcohol SCHEMBL8740660 0.86 CYP2C19 (0.54) ALDH1A1HPGDCYP2C19POLBCYP2C9
Methyl Alcohol SCHEMBL8740648 0.86 CYP2C19 (0.54) ALDH1A1HPGDCYP2C19POLBCYP2C9
SCHEMBL2551111 0.84 CYP2C19 (0.55) ALDH1A1HPGDCYP2C19POLBCYP2C9
SCHEMBL7186932 0.84 CYP2C19 (0.55) ALDH1A1HPGDCYP2C19POLBCYP2C9
SCHEMBL1881512 0.84 CYP2C19 (0.55) ALDH1A1HPGDCYP2C19POLBCYP2C9
SCHEMBL29092108 0.84 ALDH1A1 (0.52) ALDH1A1HPGDCYP2C19POLBCYP2C9
SCHEMBL17846993 0.79 BRD9 (0.41) ALDH1A1CYP2C19POLBCYP2C9CA1
SCHEMBL17846995 0.79 BRD9 (0.41) ALDH1A1CYP2C19POLBCYP2C9CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0746410-A4 WATER-SOLUBLE CHIRAL SULFONATED BINAP CATALYST FOR ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS CALIFORNIA INST OF TECHN (US) 1997-04-09 EP disclosed
EP-0746410-A1 WATER-SOLUBLE CHIRAL SULFONATED BINAP CATALYST FOR ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1996-12-11 EP disclosed
WO-1995022405-A1 WATER-SOLUBLE CHIRAL SULFONATED BINAP CATALYST FOR ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1995-08-24 WO disclosed