Methyl Alcohol

Methyl Alcohol

SCHEMBL8740642

CC(=O)Nc1ccc(C=CC(=O)O)c(C)c1.CO

nearest known ligand 0.54

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 1/20 0.54
ITGB1 P05556 1/20 0.54
ITGAV P06756 1/20 0.54
ITGA2B P08514 1/20 0.54
ITGB5 P18084 1/20 0.54
ALDH1A1 P00352 3/20 0.48
KDM4E B2RXH2 5/20 0.46
KMT2A Q03164 5/20 0.46
ENPP2 Q13822 1/20 0.46
MAPT P10636 4/20 0.45
MEN1 O00255 3/20 0.45
NPC1 O15118 3/20 0.45
RAB9A P51151 3/20 0.45
PABPC1 P11940 1/20 0.45
ESR1 P03372 1/20 0.45
LDHA P00338 1/20 0.44
GLA P06280 1/20 0.44
TNNI3 P19429 1/20 0.44
TNNT2 P45379 1/20 0.44
TNNC1 P63316 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28004254 0.98 ITGB3 (0.55) ITGB3ITGB1ITGAVITGA2BITGB5
SCHEMBL28003899 0.98 ITGB3 (0.55) ITGB3ITGB1ITGAVITGA2BITGB5
SCHEMBL9911537 0.82 ITGB3 (0.48) ITGB3ITGB1ITGAVITGA2BITGB5
SCHEMBL377917 0.79 ALDH1A1 (0.54) ALDH1A1KDM4EKMT2AENPP2MAPT
SCHEMBL29958034 0.79 ALDH1A1 (0.54) ALDH1A1KDM4EKMT2AENPP2MAPT
SCHEMBL4316794 0.78 ESR1 (0.49) ITGB3ITGB1ITGAVITGA2BITGB5
SCHEMBL13065355 0.78 ALDH1A1 (0.53) ALDH1A1KDM4EKMT2AENPP2MAPT
SCHEMBL4316791 0.78 ESR1 (0.49) ITGB3ITGB1ITGAVITGA2BITGB5
SCHEMBL13014961 0.76 ITGB3 (0.57) ITGB3ITGB1ITGAVITGA2BITGB5
SCHEMBL11315447 0.76 ESR1 (0.50) ITGB3ITGB1ITGAVITGA2BITGB5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0746410-A4 WATER-SOLUBLE CHIRAL SULFONATED BINAP CATALYST FOR ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS CALIFORNIA INST OF TECHN (US) 1997-04-09 EP disclosed
EP-0746410-A1 WATER-SOLUBLE CHIRAL SULFONATED BINAP CATALYST FOR ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1996-12-11 EP disclosed
WO-1995022405-A1 WATER-SOLUBLE CHIRAL SULFONATED BINAP CATALYST FOR ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1995-08-24 WO disclosed