Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11386724 | 0.88 | RAB9A (0.51) | RAB9AHTTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL11386719 | 0.88 | RAB9A (0.51) | RAB9AHTTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL7045635 | 0.87 | RAB9A (0.51) | RAB9AHTTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL11384770 | 0.87 | RAB9A (0.51) | RAB9AHTTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL8740701 | 0.84 | MEN1 (0.56) | RELARAB9AHTTSMN1; SMN2LMNA | |
| SCHEMBL6561252 | 0.83 | MEN1 (0.59) | RELARAB9AKMT2AMEN1POLB | |
| SCHEMBL14101483 | 0.83 | MEN1 (0.59) | RELARAB9AKMT2AMEN1POLB | |
| SCHEMBL10841638 | 0.83 | RAB9A (0.47) | RAB9AHTTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL8740680 | 0.83 | PPARG (0.40) | RELAHTTSMN1; SMN2LMNAKMT2A | |
| Iodide SCHEMBL6858468 | 0.82 | MEN1 (0.62) | RELARAB9AKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783492-A4 | PROCESS FOR THE PREPARATION OF STILBAZOLIUM SALTS | MOLECULAR OPTOELECTRONICS CORP (US) | 1997-12-03 | — | — | EP | disclosed |
| EP-0783492-A2 | PROCESS FOR THE PREPARATION OF STILBAZOLIUM SALTS | MOLECULAR OPTOELECTRONICS CORPORATION (US) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996008474-A1 | PROCESS FOR THE PREPARATION OF STILBAZOLIUM SALTS | MOLECULAR OPTOELECTRONICS CORPORATION (US) | 1996-03-21 | — | — | WO | disclosed |
| US-5360911-A | From alkylated pyridinium salt and a benzaldehyde with a pyrrolidine catalyst | GENERAL ELECTRIC COMPANY (US) | 1994-11-01 | — | — | US | disclosed |