Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8740710 | 0.83 | RELA (0.49) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL2013580 | 0.82 | MEN1 (0.43) | PPARGALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11386724 | 0.82 | RAB9A (0.51) | PPARGALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11386719 | 0.82 | RAB9A (0.51) | PPARGALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL372527 | 0.79 | CHAT (0.61) | PPARGALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9623138 | 0.76 | PPARG (0.43) | PPARGALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10398844 | 0.76 | PPARG (0.43) | PPARGALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7178000 | 0.74 | HTT (0.42) | PPARGALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11384770 | 0.74 | RAB9A (0.51) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL7045635 | 0.74 | RAB9A (0.51) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783492-A4 | PROCESS FOR THE PREPARATION OF STILBAZOLIUM SALTS | MOLECULAR OPTOELECTRONICS CORP (US) | 1997-12-03 | — | — | EP | claimed |
| EP-0783492-A2 | PROCESS FOR THE PREPARATION OF STILBAZOLIUM SALTS | MOLECULAR OPTOELECTRONICS CORPORATION (US) | 1997-07-16 | — | — | EP | claimed |
| WO-1996008474-A1 | PROCESS FOR THE PREPARATION OF STILBAZOLIUM SALTS | MOLECULAR OPTOELECTRONICS CORPORATION (US) | 1996-03-21 | — | — | WO | claimed |
| US-5360911-A | From alkylated pyridinium salt and a benzaldehyde with a pyrrolidine catalyst | GENERAL ELECTRIC COMPANY (US) | 1994-11-01 | — | — | US | claimed |
| EP-0783492-A4 | PROCESS FOR THE PREPARATION OF STILBAZOLIUM SALTS | MOLECULAR OPTOELECTRONICS CORP (US) | 1997-12-03 | — | — | EP | disclosed |
| EP-0783492-A2 | PROCESS FOR THE PREPARATION OF STILBAZOLIUM SALTS | MOLECULAR OPTOELECTRONICS CORPORATION (US) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996008474-A1 | PROCESS FOR THE PREPARATION OF STILBAZOLIUM SALTS | MOLECULAR OPTOELECTRONICS CORPORATION (US) | 1996-03-21 | — | — | WO | disclosed |
| US-5360911-A | From alkylated pyridinium salt and a benzaldehyde with a pyrrolidine catalyst | GENERAL ELECTRIC COMPANY (US) | 1994-11-01 | — | — | US | disclosed |