Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CCR6 | P51684 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CCR2 | P41597 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CCR4 | P51679 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10502108 | 0.86 | MEN1 (0.54) | HPGDHPSEMAPTPOLBSLC25A1 | |
| SCHEMBL3834884 | 0.86 | HPSE (0.55) | HPGDHPSEMAPTLMNAPOLB | |
| SCHEMBL8075212 | 0.85 | TDP1 (0.51) | HPGDMAPTLMNAPOLBCCR6 | |
| SCHEMBL18641353 | 0.83 | MEN1 (0.48) | HPGDHPSEMAPTLMNAPOLB | |
| SCHEMBL9263396 | 0.83 | ESR2 (0.62) | HPGDHPSEMAPTPOLBHTT | |
| SCHEMBL28090366 | 0.82 | TDP1 (0.55) | HPGDHPSEMAPTLMNASLC25A1 | |
| SCHEMBL4002257 | 0.82 | HPSE (0.67) | HPSEMAPTLMNAPOLBHTT | |
| SCHEMBL3840523 | 0.82 | HPSE (0.56) | HPSEMAPTLMNAPOLBCCR6 | |
| SCHEMBL4697145 | 0.81 | KMT2A (0.54) | HPGDMAPTLMNANPSR1GPR55 | |
| SCHEMBL8075197 | 0.81 | HPSE (0.55) | HPGDHPSEMAPTLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799198-A4 | — | — | 1997-10-15 | — | — | EP | disclosed |
| EP-0799198-A1 | ANTI-INFLAMMATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-10-08 | — | — | EP | disclosed |
| WO-1995033461-A1 | ANTI-INFLAMMATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-12-14 | — | — | WO | disclosed |