SCHEMBL8740808

SCHEMBL8740808

CN(C)c1ccccc1OCCCl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 3/20 0.42
TDP1 Q9NUW8 2/20 0.42
HTR1B P28222 3/20 0.39
ADRB2 P07550 1/20 0.38
ADRB1 P08588 1/20 0.38
KDM4E B2RXH2 3/20 0.37
ALDH1A1 P00352 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
DRD2 P14416 1/20 0.37
DRD1 P21728 1/20 0.37
DRD4 P21917 1/20 0.37
DRD5 P21918 1/20 0.37
HRH1 P35367 1/20 0.36
JAK2 O60674 1/20 0.35
LMNA P02545 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15966175 0.82 CYP1A2 (0.44) HTR7TDP1HTR1BMAPTCYP1A2
SCHEMBL12646498 0.81 HTR7 (0.46) HTR7TDP1HTR1BADRB2ADRB1
SCHEMBL15965350 0.79 TDP1 (0.41) HTR7TDP1HTR1BDRD2DRD1
SCHEMBL7410921 0.79 TDP1 (0.41) HTR7TDP1HTR1BDRD2DRD1
SCHEMBL6848695 0.79 KDM4E (0.54) HTR7TDP1KDM4EALDH1A1SMN1; SMN2
SCHEMBL10490480 0.78 MEN1 (0.51) HTR1BALDH1A1LMNAMAPTCYP1A2
SCHEMBL2863207 0.78 ALDH1A1 (0.52) TDP1ALDH1A1LMNAGAAMAPT
SCHEMBL14320203 0.77 ALDH1A1 (0.43) HTR7TDP1HTR1BADRB2ADRB1
SCHEMBL22736929 0.77 TDP1 (0.39) HTR7TDP1HTR1BALDH1A1SMN1; SMN2
Hydrochloric Acid SCHEMBL2863204 0.76 ALDH1A1 (0.50) TDP1ALDH1A1LMNAGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119874681-A Indole derivative, preparation method thereof and application of indole derivative in resisting liver cancer 中国人民解放军北部战区总医院 2025-04-25 CN disclosed
US-5683856-A CATIONIC AMMONIUM RESIN, ACID GENERATOR, DISSOLUTION INHIBITION FUJI PHOTO FILM CO., LTD. (JP) 1997-11-04 US disclosed
EP-0708368-A1 Positive-working photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1996-04-24 EP disclosed