SCHEMBL8740836

SCHEMBL8740836

CCNC(=O)/C=C/c1cccc(O)c1

nearest known ligand 0.77

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC6A19 Q695T7 1/20 0.71
MMP1 P03956 16/20 0.68
MMP2 P08253 16/20 0.68
MMP9 P14780 16/20 0.68
NOS2 P35228 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8740837 1.00 SLC6A19 (0.71) SLC6A19MMP1MMP2MMP9NOS2
SCHEMBL8740838 1.00 SLC6A19 (0.71) SLC6A19MMP1MMP2MMP9NOS2
SCHEMBL27542057 0.85 MMP1 (0.66) MMP1MMP2MMP9
SCHEMBL8757222 0.83 EGFR (0.73) MMP1MMP2MMP9
SCHEMBL8757218 0.83 EGFR (0.73) MMP1MMP2MMP9
SCHEMBL8756520 0.83 EGFR (0.73) MMP1MMP2MMP9
SCHEMBL8756506 0.83 EGFR (0.73) MMP1MMP2MMP9
SCHEMBL8756511 0.83 EGFR (0.73) MMP1MMP2MMP9
SCHEMBL8757229 0.83 EGFR (0.73) MMP1MMP2MMP9
SCHEMBL25193471 0.83 MMP1 (0.71) MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0677058-A4 SUPPORT AND METHOD FOR IMMOBILIZING POLYPEPTIDES. APPLIED BIOSYSTEMS (US) 1997-09-24 EP claimed
US-5602207-A A POLYVINYLIDENE FLUORIDE MEMBRANE HAVING SURFACE-ATTACHED ENOL ESTER GROUPS AND SURFACE ATTACHED SULFONATE GROUPS THE PERKIN-ELMER CORPORATION (US) 1997-02-11 US claimed
EP-0677058-A1 SUPPORT AND METHOD FOR IMMOBILIZING POLYPEPTIDES THE PERKIN-ELMER CORPORATION (US) 1995-10-18 EP claimed
WO-1994015948-A1 SUPPORT AND METHOD FOR IMMOBILIZING POLYPEPTIDES APPLIED BIOSYSTEMS, INC. (US) 1994-07-21 WO claimed