Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT2 | P31751 | 3/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9459084 | 0.80 | HTT (0.50) | AKT2CHEK1KMT2APDGFRAMAPK8 | |
| SCHEMBL9458570 | 0.80 | MDM2 (0.41) | AKT2CHEK1KMT2AATMPDGFRA | |
| SCHEMBL13818944 | 0.77 | NOTUM (0.44) | ATMNOTUMERN1 | |
| SCHEMBL5413929 | 0.77 | KMO (0.51) | KMT2AGAANOTUMLMNAMAPT | |
| SCHEMBL5401610 | 0.77 | TTR (0.49) | NOTUMALDH1A1 | |
| SCHEMBL24697157 | 0.74 | AKT2 (0.39) | AKT2CHEK1KMT2APDGFRAMAPK8 | |
| SCHEMBL1585807 | 0.74 | RPA1 (0.51) | KMT2AHTTGAANOTUMLMNA | |
| SCHEMBL12670780 | 0.74 | CHUK (0.47) | AKT2CHEK1CDK5HTTGAA | |
| SCHEMBL28281518 | 0.71 | MAPK14 (0.42) | MAPTPTGS1PTGS2 | |
| SCHEMBL22391489 | 0.69 | MAPT (0.48) | AKT2CHEK1KMT2AHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109503452-B | Preparation method of 2,3, 4-trisubstituted pyrrole derivative | 华侨大学 | 2021-11-02 | — | — | CN | disclosed |
| CN-109503452-A | A kind of preparation method of tri- substituted azole derivatives of 2,3,4- | 华侨大学 | 2019-03-22 | — | — | CN | disclosed |
| EP-0684950-A4 | CHEMICAL COMPOUNDS USEFUL IN PHOTODYNAMIC THERAPY AND PRODUCTION OF LASER LIGHT. | BO DEKK VENTURES LTD (US) | 1997-10-15 | — | — | EP | disclosed |
| EP-0684950-A1 | CHEMICAL COMPOUNDS USEFUL IN PHOTODYNAMIC THERAPY AND PRODUCTION OF LASER LIGHT | BO-DEKK VENTURES, LTD. (US) | 1995-12-06 | — | — | EP | disclosed |
| US-5446157-A | Boron difluoride compounds useful in photodynamic therapy and production of laser light | BO-DEKK VENTURES, LTD. | 1995-08-29 | — | — | US | disclosed |
| WO-1994019355-A1 | CHEMICAL COMPOUNDS USEFUL IN PHOTODYNAMIC THERAPY AND PRODUCTION OF LASER LIGHT | BO-DEKK VENTURES, LTD. (US) | 1994-09-01 | — | — | WO | disclosed |