Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456879 | 0.92 | ALDH1A1 (0.59) | ALDH1A1TSHRTBXAS1THRBFNTA | |
| SCHEMBL523127 | 0.90 | ALDH1A1 (0.63) | ALDH1A1TSHRTBXAS1THRBFNTA | |
| SCHEMBL16292006 | 0.90 | ALDH1A1 (0.63) | ALDH1A1TSHRTBXAS1THRBFNTA | |
| SCHEMBL16291990 | 0.90 | ALDH1A1 (0.63) | ALDH1A1TSHRTBXAS1THRBFNTA | |
| SCHEMBL16291638 | 0.90 | ALDH1A1 (0.63) | ALDH1A1TSHRTBXAS1THRBFNTA | |
| SCHEMBL156151 | 0.86 | ALDH1A1 (0.50) | ALDH1A1TSHRTBXAS1KDM4ELMNA | |
| SCHEMBL13684994 | 0.85 | ALDH1A1 (0.52) | ALDH1A1TSHRTBXAS1KDM4EEPHX2 | |
| SCHEMBL13685002 | 0.85 | ALDH1A1 (0.52) | ALDH1A1TSHRTBXAS1KDM4EEPHX2 | |
| Methacrylic Acid SCHEMBL9452621 | 0.84 | ALDH1A1 (0.39) | ALDH1A1TSHRTHRB | |
| SCHEMBL14659937 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TSHRTBXAS1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698372-A | PIGMENT DISPERSED IN PRESENCE OF POLYMER HAVING ALIPHATIC DOUBLE BOND IN SIDE CHAIN | FUJI PHOTO FILM CO., LTD. (JP) | 1997-12-16 | — | — | US | disclosed |