⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 5-Bromouracil SCHEMBL30790330 | 1.00 | — | — | |
| SCHEMBL1853388 | 0.75 | — | — | |
| SCHEMBL2183234 | 0.75 | — | — | |
| SCHEMBL16225639 | 0.75 | — | — | |
| SCHEMBL6207922 | 0.75 | — | — | |
| SCHEMBL149516 | 0.72 | — | — | |
| Water SCHEMBL29599612 | 0.70 | — | — | |
| SCHEMBL23674421 | 0.70 | — | — | |
| SCHEMBL30519898 | 0.70 | MBOAT4 (0.35) | — | |
| SCHEMBL29038044 | 0.70 | GABRA1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233665-A1 | COMPOUNDS AND THEIR USE AGAINST CANCER | TANGO THERAPEUTICS, INC. (US) | 2024-11-14 | — | — | WO | disclosed |
| US-20240226107-A1 | UBIQUITIN-SPECIFIC PROTEASE 1 (USP1) INHIBITOR | HAINAN SIMCERE ZAIMING PHARMACEUTICAL CO., LTD. (CN) | 2024-07-11 | — | — | US | disclosed |
| US-20240226107-A1 | UBIQUITIN-SPECIFIC PROTEASE 1 (USP1) INHIBITOR | HAINAN SIMCERE ZAIMING PHARMACEUTICAL CO., LTD. (CN) | 2024-07-11 | — | — | US | disclosed |
| CN-114929707-B | EED inhibitor and preparation method and application thereof | 上海科技大学 | 2024-04-09 | — | — | CN | disclosed |
| US-20240059689-A1 | PURINE DERIVATIVES AS ANTICANCER AGENTS | MEDIVIR AB (SE) | 2024-02-22 | — | — | US | disclosed |
| EP-4308566-A1 | PURINE DERIVATIVES AS ANTICANCER AGENTS | Tango Therapeutics, Inc. (US) | 2024-01-24 | — | — | EP | disclosed |
| CN-117425656-A | Purine derivatives as anticancer agents | 探戈医药股份有限公司 | 2024-01-19 | — | — | CN | disclosed |
| US-20230028221-A1 | EED INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | JING MEDICINE TECHNOLOGY (SHANGHAI) LTD. (CN) | 2023-01-26 | — | — | US | disclosed |
| WO-2022197892-A1 | PURINE DERIVATIVES AS ANTICANCER AGENTS | TANGO THERAPEUTICS, INC. (US) | 2022-09-22 | — | — | WO | disclosed |
| WO-2021083380-A1 | EED INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海科技大学 | 2021-05-06 | — | — | WO | disclosed |
| EP-0586523-A4 | DETERMINATION OF PRODRUGS METABOLIZABLE BY THE LIVER AND THERAPEUTIC USE THEREOF | UNIV YALE (US) | 1995-11-29 | — | — | EP | disclosed |
| EP-0586523-A1 | DETERMINATION OF PRODRUGS METABOLIZABLE BY THE LIVER AND THERAPEUTIC USE THEREOF | YALE UNIVERSITY (US) | 1994-03-16 | — | — | EP | disclosed |
| EP-0567126-A1 | Processing composition for silver halide photographic material and processing method using same | FUJI PHOTO FILM CO., LTD. (JP) | 1993-10-27 | — | — | EP | disclosed |
| US-5213972-A | Production of thymidine and deoxyuridine, intermediates for AZT | CHEMGEN CORPORATION (US) | 1993-05-25 | — | — | US | disclosed |
| WO-1992020816-A1 | DETERMINATION OF PRODRUGS METABOLIZABLE BY THE LIVER AND THERAPEUTIC USE THEREOF | YALE UNIVERSITY (US) | 1992-11-26 | — | — | WO | disclosed |
| US-5147765-A | Desilvering; stability, discoloration inhibition | FUJI PHOTO FILM CO., LTD. (JP) | 1992-09-15 | — | — | US | disclosed |
| EP-0427204-A1 | Method for processing silver halide colour photographic materials | Fuji Photo Film Co., Ltd. (JP) | 1991-05-15 | — | — | EP | disclosed |
| US-4447605-A | Di(tri-lower alkylstannyl)pyrimidine derivative and a process for producing the same | RIKAGAKU KENKYUSHO (JP) | 1984-05-08 | — | — | US | disclosed |
| US-4430495-A | Process for preparing lincomycin and clindamycin ribonucleotides | THE UPJOHN COMPANY (US) | 1984-02-07 | — | — | US | disclosed |
| US-4324895-A | REACTION BETWEEN BIS(TRI-LOWER ALKYLSTANNYL)-5-HALOGENOURACIL AND 2-SUBSTITUTED TETRAHYDROFURAN | RIKAGAKU KENKYUSHO (JP) | 1982-04-13 | — | — | US | disclosed |