Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL882997 | 0.86 | P2RX7 (0.37) | HSP90AA1P2RX7NPC1RAB9AMEN1 | |
| SCHEMBL10272873 | 0.84 | HSP90AA1 (0.36) | HSP90AA1P2RX7NPC1RAB9AMEN1 | |
| SCHEMBL882996 | 0.84 | HSP90AA1 (0.35) | HSP90AA1P2RX7NPC1RAB9AMEN1 | |
| SCHEMBL16164228 | 0.84 | HSP90AA1 (0.35) | HSP90AA1P2RX7NPC1RAB9AMEN1 | |
| SCHEMBL874610 | 0.81 | HSP90AA1 (0.35) | HSP90AA1P2RX7MEN1KMT2AHKDC1 | |
| SCHEMBL13545605 | 0.81 | HSP90AA1 (0.43) | HSP90AA1P2RX7NPC1RAB9AHKDC1 | |
| SCHEMBL12467180 | 0.77 | HSP90AA1 (0.34) | HSP90AA1P2RX7MEN1KMT2AHKDC1 | |
| SCHEMBL874223 | 0.77 | HSP90AA1 (0.33) | HSP90AA1P2RX7HKDC1 | |
| SCHEMBL874106 | 0.75 | P2RX7 (0.41) | HSP90AA1P2RX7NPC1RAB9AMEN1 | |
| SCHEMBL10273706 | 0.73 | HSP90AA1 (0.35) | HSP90AA1P2RX7MEN1KMT2AHKDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619181-A1 | NOVEL MICROBIOCIDES | Syngenta Participations AG (CH) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038521-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-03-29 | — | — | WO | disclosed |