Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 12/20 | 0.51 |
| ▸ | MMP9 | P14780 | 12/20 | 0.51 |
| ▸ | MMP3 | P08254 | 2/20 | 0.49 |
| ▸ | MMP13 | P45452 | 2/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503724 | 0.88 | MMP2 (0.47) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL7079889 | 0.84 | MMP2 (0.49) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL27516002 | 0.83 | MMP2 (0.48) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL7080833 | 0.82 | ALDH1A1 (0.58) | MMP2MMP9MMP3MMP13CA12 | |
| SCHEMBL9219366 | 0.81 | MMP2 (0.55) | MMP2MMP9MMP3MMP13CA12 | |
| SCHEMBL7865124 | 0.81 | TSHR (0.58) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL7342436 | 0.79 | MMP2 (0.52) | MMP2MMP9MMP3MMP13CA12 | |
| SCHEMBL8525115 | 0.79 | MMP2 (0.45) | MMP2MMP9SMN1; SMN2 | |
| SCHEMBL8474689 | 0.79 | MMP2 (0.45) | MMP2MMP9SMN1; SMN2 | |
| SCHEMBL8475447 | 0.79 | MMP2 (0.45) | MMP2MMP9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790974-A1 | SUBSTITUTED 4-BIARYLBUTYRIC OR 5-BIARYLPENTANOIC ACIDS AND DERIVATIVES AS MATRIX METALLOPROTEASE INHIBITIORS | Bayer Corporation (US) | 1997-08-27 | — | — | EP | claimed |