SCHEMBL874209

SCHEMBL874209

C=C(C)C(=O)OCCS(=O)(=O)CC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
TSHR P16473 3/20 0.44
POLB P06746 2/20 0.41
APEX1 P27695 2/20 0.38
HTT P42858 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 2/20 0.36
MMP12 P39900 1/20 0.33
MMP13 P45452 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13113085 0.90 TSHR (0.50) THRBTSHRPOLBAPEX1HTT
SCHEMBL9228965 0.87 THRB (0.53) THRBTSHRPOLBAPEX1HTT
SCHEMBL9070045 0.84 APEX1 (0.52) THRBTSHRPOLBAPEX1HTT
SCHEMBL3291007 0.83 THRB (0.55) THRBTSHRPOLBAPEX1HTT
SCHEMBL12891194 0.81 POLB (0.48) TSHRPOLBAPEX1ALDH1A1MMP12
SCHEMBL9316932 0.80 THRB (0.47) THRBTSHRPOLBAPEX1HTT
SCHEMBL5872171 0.80 TSHR (0.55) THRBTSHRPOLBAPEX1HTT
SCHEMBL434886 0.79 THRB (0.50) THRBTSHRPOLBAPEX1HTT
SCHEMBL882495 0.79 THRB (0.40) THRBTSHRPOLBAPEX1HTT
SCHEMBL10901127 0.79 THRB (0.46) THRBTSHRPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11059990-B2 Anti-fouling coatings METASHIELD LLC (US) 2021-07-13 US claimed
WO-2020081253-A1 ANTI-FOULING COATINGS METASHIELD LLC (US) 2020-04-23 WO claimed
US-20200115583-A1 ANTI-FOULING COATINGS METASHIELD LLC 2020-04-16 US claimed
US-11059990-B2 Anti-fouling coatings METASHIELD LLC (US) 2021-07-13 US disclosed
WO-2020081253-A1 ANTI-FOULING COATINGS METASHIELD LLC (US) 2020-04-23 WO disclosed
US-20200115583-A1 ANTI-FOULING COATINGS METASHIELD LLC 2020-04-16 US disclosed
EP-2618845-B1 TUNABLE, BIODEGRADABLE LINKER MOLECULES FOR TRANSIENT CONJUGATION OF COMPONENTS IN DRUG DELIVERY SYSTEMS, AND DRUG DELIVERY SYSTEMS PREPARED THEREWITH CRISTAL DELIVERY B V (NL) 2020-02-26 EP disclosed
US-20190298855-A1 NANOPARTICLES WITH ACTIVE TARGETING CRISTAL DELIVERY B.V. (NL) 2019-10-03 US disclosed
EP-3377047-A1 NANOPARTICLES WITH ACTIVE TARGETING Cristal Delivery B.V. (NL) 2018-09-26 EP disclosed
CN-108463217-A Nano particle with active targeting 克里斯特递送有限公司 2018-08-28 CN disclosed
US-9339554-B2 Tunable, biodegradable linker molecules for transient conjugation of components in drug delivery systems, and drug delivery systems prepared therewith CRISTAL DELIVERY B.V. (NL) 2016-05-17 US disclosed
WO-2012039602-A1 TUNABLE, BIODEGRADABLE LINKER MOLECULES FOR TRANSIENT CONJUGATION OF COMPONENTS IN DRUG DELIVERY SYSTEMS, AND DRUG DELIVERY SYSTEMS PREPARED THEREWITH UNIVERSITEIT UTRECHT HOLDING B.V. (NL) 2012-03-29 WO disclosed
US-7438950-B2 Metallic pattern forming method and conductive pattern material FUJIFILM CORPORATION (JP) 2008-10-21 US disclosed
US-7306895-B2 Pattern forming method, image forming method, fine particle adsorption pattern forming method, conductive pattern forming method, pattern forming material and planographic printing plate FUJIFILM CORPORATION (JP) 2007-12-11 US disclosed
US-7306895-B2 Pattern forming method, image forming method, fine particle adsorption pattern forming method, conductive pattern forming method, pattern forming material and planographic printing plate FUJIFILM CORPORATION (JP) 2007-12-11 US disclosed
US-20070246249-A1 Metal Pattern Forming Methd, Metal Pattern Obtained by the Same, Printed Wiring Board, Conductive Film Forming Method, and Conductive Film Obtained by the Same FUJI PHOTO FILM CO., LTD. (JP) 2007-10-25 US disclosed
US-7279195-B2 Method of forming metal fine particle pattern and method of forming electroconductive pattern FUJIFILM CORPORATION (JP) 2007-10-09 US disclosed
US-7279195-B2 Method of forming metal fine particle pattern and method of forming electroconductive pattern FUJIFILM CORPORATION (JP) 2007-10-09 US disclosed
US-7157193-B2 Image forming material, color filter master plate, and color filter FUJI PHOTO FILM CO., LTD. (JP) 2007-01-02 US disclosed
US-7157193-B2 Image forming material, color filter master plate, and color filter FUJI PHOTO FILM CO., LTD. (JP) 2007-01-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190298855-A1 NANOPARTICLES WITH ACTIVE TARGETING CD47, FCGR2A, NAPA THRB 3090/4885TSHR 2458/4885POLB 2798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.