Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9228965 | 0.89 | THRB (0.53) | APEX1THRBTSHRHTTPOLB | |
| SCHEMBL874209 | 0.84 | THRB (0.46) | APEX1THRBTSHRHTTPOLB | |
| SCHEMBL5872171 | 0.82 | TSHR (0.55) | APEX1THRBTSHRHTTPOLB | |
| SCHEMBL9316932 | 0.82 | THRB (0.47) | APEX1THRBTSHRHTTPOLB | |
| SCHEMBL3291007 | 0.82 | THRB (0.55) | APEX1THRBTSHRHTTPOLB | |
| SCHEMBL10894924 | 0.81 | THRB (0.46) | APEX1THRBTSHRHTTPOLB | |
| SCHEMBL10901127 | 0.81 | THRB (0.46) | APEX1THRBTSHRHTTPOLB | |
| SCHEMBL9221212 | 0.80 | THRB (0.39) | APEX1THRBTSHRHTTPOLB | |
| SCHEMBL5872286 | 0.79 | TSHR (0.61) | APEX1THRBTSHRHTTPOLB | |
| Succinic Acid SCHEMBL5426323 | 0.79 | THRB (0.61) | APEX1THRBTSHRHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587499-A | SIMPLE, EFFICIENT | ELF ATOCHEM S.A. (FR) | 1996-12-24 | — | — | US | disclosed |
| US-5457172-A | An alkoxycarbonylalkylthio(or sulfone or sulfoxide) alkyl acrylate monomer; homo- and copolymers; molding materials; castings; binders; coating vehicles | ELF ATOCHEM S.A. (FR) | 1995-10-10 | — | — | US | disclosed |