Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | SLC9A1 | P19634 | 5/20 | 0.49 |
| ▸ | PLAU | P00749 | 3/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | TPH1 | P17752 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8742121 | 0.98 | GSK3B (0.48) | GSK3BSLC9A1PLAUHTR7HTR2B | |
| SCHEMBL8506116 | 0.79 | PLAU (0.50) | SLC9A1PLAUHTR7HTR2BDRD2 | |
| Hydrochloric Acid SCHEMBL8506408 | 0.78 | PLAU (0.49) | SLC9A1PLAUHTR7HTR2BDRD2 | |
| Hydrochloric Acid SCHEMBL8955331 | 0.74 | SLC9A1 (0.51) | SLC9A1PLAUHTR7HTR2BGAA | |
| Hydrochloric Acid SCHEMBL8956377 | 0.74 | SLC9A1 (0.44) | SLC9A1HTR7HTR2B | |
| SCHEMBL8446271 | 0.74 | SLC9A1 (0.41) | SLC9A1PLAUHTR7HTR2BTPH1 | |
| SCHEMBL5981761 | 0.73 | GSK3B (0.61) | GSK3BGAAMAPTCA1CA2 | |
| Hydrochloric Acid SCHEMBL8831783 | 0.73 | SLC9A1 (0.40) | SLC9A1PLAUHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL8443394 | 0.73 | SLC9A1 (0.40) | SLC9A1PLAUHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL8506241 | 0.73 | SLC9A1 (0.54) | SLC9A1HTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603650-B1 | 3,5-Substituted amino benzoylguanidines, process for their preparation, their use as medicine or diagnostic agent, as well as a medicine containing them | HOECHST AG (DE) | 1997-04-02 | — | — | EP | claimed |