Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 3/20 | 0.41 |
| ▸ | PLAU | P00749 | 3/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | TPH1 | P17752 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8443394 | 0.98 | SLC9A1 (0.40) | SLC9A1PLAUTTRF2F10 | |
| SCHEMBL8446639 | 0.81 | SLC9A1 (0.44) | SLC9A1TTRHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL8443013 | 0.80 | SLC9A1 (0.43) | SLC9A1TTRHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL8639710 | 0.80 | TSHR (0.46) | SLC9A1PLAU | |
| SCHEMBL13449170 | 0.79 | TTR (0.48) | PLAUTTRF2F10PLG | |
| Hydrochloric Acid SCHEMBL8643356 | 0.77 | SLC9A1 (0.36) | SLC9A1PLAUTPH1 | |
| SCHEMBL1638962 | 0.76 | TTR (0.67) | TTRAKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL8742205 | 0.74 | GSK3B (0.50) | SLC9A1PLAUTPH1HTR7HTR2B | |
| SCHEMBL8446223 | 0.74 | HTR2B (0.45) | SLC9A1TPH1HTR7HTR2B | |
| Hydrochloric Acid SCHEMBL8742121 | 0.73 | GSK3B (0.48) | SLC9A1PLAUHTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0628543-B1 | Substituted benzoylguanidines, process for their preparation, their use as medicament or diagnostic agent, as well as a medicament containing them | HOECHST AG (DE) | 1999-06-16 | — | — | EP | claimed |