Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15955988 | 0.82 | CTDSP1 (0.37) | CA2CTDSP1 | |
| SCHEMBL15955749 | 0.81 | CTDSP1 (0.36) | CA2CTDSP1 | |
| SCHEMBL17854784 | 0.81 | CTDSP1 (0.35) | CA2LMNACTDSP1 | |
| SCHEMBL1411292 | 0.80 | MEN1 (0.31) | MEN1LMNAKMT2ACTDSP1CHRM2 | |
| SCHEMBL28544297 | 0.80 | MEN1 (0.31) | CA2MEN1LMNAKMT2ACHRM2 | |
| SCHEMBL9598615 | 0.80 | MEN1 (0.31) | MEN1LMNAKMT2ACTDSP1CHRM2 | |
| SCHEMBL9597774 | 0.80 | MEN1 (0.31) | MEN1LMNAKMT2ACTDSP1CHRM2 | |
| SCHEMBL15955777 | 0.79 | CTDSP1 (0.38) | CA2CTDSP1 | |
| SCHEMBL15956025 | 0.79 | CTDSP1 (0.40) | CA2CTDSP1 | |
| SCHEMBL14457875 | 0.78 | CA2 (0.38) | CA2TSHRMAPK1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9020772-A | — | — | None | — | — | JP | disclosed |
| US-20150291567-A1 | TRANSKETALIZED COMPOSITIONS, SYNTHESIS, AND APPLICATIONS | GFBIOCHEMICALS LIMITED (MT) | 2015-10-15 | — | — | US | disclosed |
| US-20150291567-A1 | TRANSKETALIZED COMPOSITIONS, SYNTHESIS, AND APPLICATIONS | GFBIOCHEMICALS LIMITED (MT) | 2015-10-15 | — | — | US | disclosed |
| US-20140135455-A1 | TRANSKETALIZED COMPOSITIONS, SYNTHESIS, AND APPLICATIONS | SEGETIS, INC. (US) | 2014-05-15 | — | — | US | disclosed |
| US-20140135455-A1 | TRANSKETALIZED COMPOSITIONS, SYNTHESIS, AND APPLICATIONS | SEGETIS, INC. (US) | 2014-05-15 | — | — | US | disclosed |
| US-8653223-B2 | Transketalized compositions, synthesis, and applications | SEGETIS, INC. (US) | 2014-02-18 | — | — | US | disclosed |
| US-8653223-B2 | Transketalized compositions, synthesis, and applications | SEGETIS, INC. (US) | 2014-02-18 | — | — | US | disclosed |
| US-20110082264-A1 | TRANSKETALIZED COMPOSITIONS, SYNTHESIS, AND APPLICATIONS | SEGETIS, INC. (US) | 2011-04-07 | — | — | US | disclosed |
| US-20110082264-A1 | TRANSKETALIZED COMPOSITIONS, SYNTHESIS, AND APPLICATIONS | SEGETIS, INC. (US) | 2011-04-07 | — | — | US | disclosed |
| WO-2009146202-A2 | TRANSKETALIZED COMPOSITIONS, SYNTHESIS, AND APPLICATIONS | SEGETIS, INC. (US) | 2009-12-03 | — | — | WO | disclosed |
| JP-H0920772-A | CYCLIC ACETAL AND ITS PRODUCTION | KAO CORP | 1997-01-21 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140135455-A1 | TRANSKETALIZED COMPOSITIONS, SYNTHESIS, AND APPLICATIONS | TKT, KHK, KYAT3 | CA2 3989/4885TSHR 4819/4885MAPK1 4036/4885 |
| US-20110082264-A1 | TRANSKETALIZED COMPOSITIONS, SYNTHESIS, AND APPLICATIONS | TKT, KHK, KYAT3 | CA2 3989/4885TSHR 4819/4885MAPK1 4036/4885 |
| US-20150291567-A1 | TRANSKETALIZED COMPOSITIONS, SYNTHESIS, AND APPLICATIONS | TKT, KHK, KYAT3 | CA2 3989/4885TSHR 4819/4885MAPK1 4036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.