Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845350 | 0.91 | MAPK1 (0.49) | MAPK1LMNACYP2C9CYP2C19GAA | |
| SCHEMBL10119639 | 0.88 | MEN1 (0.46) | MAPK1LMNACYP2C9CYP2C19GAA | |
| SCHEMBL874056 | 0.88 | TRPV1 (0.42) | MAPK1CYP2C9CYP2C19ALDH1A1HTT | |
| SCHEMBL874311 | 0.88 | ALDH1A1 (0.47) | LMNACYP2C9CYP2C19ALDH1A1HDAC3 | |
| SCHEMBL874313 | 0.87 | MAPK1 (0.50) | MAPK1LMNACYP2C9CYP2C19GAA | |
| SCHEMBL10119551 | 0.86 | DHODH (0.40) | CYP2C9CYP2C19GAAALDH1A1TRPV1 | |
| SCHEMBL10119315 | 0.86 | MAPT (0.40) | MAPK1CYP2C9CYP2C19ALDH1A1HTT | |
| SCHEMBL10119344 | 0.86 | CYP2C9 (0.39) | MAPK1CYP2C9CYP2C19ALDH1A1HTT | |
| SCHEMBL872532 | 0.86 | TRPV1 (0.44) | MAPK1CYP2C9CYP2C19ALDH1A1HTT | |
| SCHEMBL10119502 | 0.86 | CYP2C9 (0.39) | MAPK1CYP2C9CYP2C19ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |