Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | PNP | P00491 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | EDNRA | P25101 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | HBB | P68871 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | VCP | P55072 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | HPRT1 | P00492 | 11/20 | 0.53 |
| ▸ | TK1 | P04183 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29325413 | 0.83 | BLM (0.59) | BLMPNPUSP2TSHREDNRA | |
| SCHEMBL5653744 | 0.83 | BLM (0.59) | BLMPNPUSP2TSHREDNRA | |
| SCHEMBL8540040 | 0.83 | BLM (0.58) | BLMPNPUSP2TSHREDNRA | |
| SCHEMBL19249139 | 0.83 | PNP (0.50) | BLMPNPUSP2TSHREDNRA | |
| SCHEMBL8743548 | 0.83 | PNP (0.55) | BLMPNPUSP2TSHREDNRA | |
| SCHEMBL8743536 | 0.82 | PNP (0.51) | BLMPNPUSP2TSHREDNRA | |
| SCHEMBL9827056 | 0.79 | BLM (0.53) | BLMPNPUSP2TSHREDNRA | |
| SCHEMBL25611139 | 0.79 | PNP (0.53) | BLMPNPUSP2TSHREDNRA | |
| SCHEMBL29174355 | 0.78 | HPRT1 (0.55) | BLMPNPUSP2TSHREDNRA | |
| SCHEMBL10819843 | 0.78 | BLM (0.52) | BLMPNPUSP2TSHREDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335770-B1 | Novel fluorophosphonate nucleotide derivatives | MERRELL PHARMA INC (US) | 1997-01-15 | — | — | EP | disclosed |
| EP-0339161-A1 | Novel fluorophosphonate nucleotide derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-11-02 | — | — | EP | disclosed |
| EP-0335770-A2 | Novel fluorophosphonate nucleotide derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1989-10-04 | — | — | EP | disclosed |