Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.59 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.59 |
| ▸ | PGK1 | P00558 | 3/20 | 0.38 |
| ▸ | PGK2 | P07205 | 3/20 | 0.38 |
| ▸ | FDPS | P14324 | 4/20 | 0.33 |
| ▸ | PNP | P00491 | 4/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1533877 | 0.78 | LPAR1 (0.83) | LPAR1LPAR3FDPSGGPS1 | |
| SCHEMBL6154740 | 0.78 | LPAR1 (0.57) | LPAR1LPAR3PGK1PGK2FDPS | |
| SCHEMBL1533943 | 0.76 | LPAR1 (0.96) | LPAR1LPAR3FDPSGGPS1 | |
| SCHEMBL15110889 | 0.76 | LPAR1 (0.45) | LPAR1LPAR3PGK1PGK2FDPS | |
| SCHEMBL9109027 | 0.76 | LPAR1 (0.61) | LPAR1LPAR3PGK1PGK2FDPS | |
| SCHEMBL193245 | 0.75 | LPAR1 (1.00) | LPAR1LPAR3FDPSGGPS1 | |
| SCHEMBL18720921 | 0.75 | LPAR1 (0.59) | LPAR1LPAR3PGK1PGK2FDPS | |
| SCHEMBL9110451 | 0.75 | LPAR1 (0.64) | LPAR1LPAR3PGK1PGK2FDPS | |
| SCHEMBL10090904 | 0.73 | LPAR1 (0.42) | LPAR1LPAR3PGK1PGK2PTPN2 | |
| SCHEMBL1585488 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335770-B1 | Novel fluorophosphonate nucleotide derivatives | MERRELL PHARMA INC (US) | 1997-01-15 | — | — | EP | disclosed |
| EP-0335770-A2 | Novel fluorophosphonate nucleotide derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1989-10-04 | — | — | EP | disclosed |