Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.64 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.64 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.38 |
| ▸ | FDPS | P14324 | 10/20 | 0.36 |
| ▸ | PNP | P00491 | 3/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.35 |
| ▸ | PGK1 | P00558 | 1/20 | 0.34 |
| ▸ | PGK2 | P07205 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9109027 | 0.98 | LPAR1 (0.61) | LPAR1LPAR3GGPS1FDPSPNP | |
| SCHEMBL193245 | 0.78 | LPAR1 (1.00) | LPAR1LPAR3GGPS1FDPSSMPD1 | |
| SCHEMBL1533943 | 0.76 | LPAR1 (0.96) | LPAR1LPAR3GGPS1FDPSSMPD1 | |
| SCHEMBL6666067 | 0.76 | FDPS (0.63) | LPAR1LPAR3GGPS1FDPSSMPD1 | |
| SCHEMBL9514697 | 0.75 | LPAR1 (0.46) | LPAR1LPAR3GGPS1FDPS | |
| SCHEMBL8743575 | 0.75 | LPAR1 (0.59) | LPAR1LPAR3GGPS1FDPSPNP | |
| SCHEMBL1533877 | 0.73 | LPAR1 (0.83) | LPAR1LPAR3GGPS1FDPSSMPD1 | |
| SCHEMBL6666195 | 0.73 | FDPS (0.61) | GGPS1FDPS | |
| SCHEMBL6154740 | 0.73 | LPAR1 (0.57) | LPAR1LPAR3GGPS1FDPSPNP | |
| SCHEMBL1527593 | 0.71 | PNP (0.42) | LPAR1LPAR3PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459216-A2 | IMMUNOGENIC COMPOSITIONS INCLUDING TLR ACTIVITY MODULATORS | Novartis AG (CH) | 2012-06-06 | — | — | EP | disclosed |