Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.61 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.61 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | PGK2 | P07205 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 11/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.34 |
| ▸ | PNP | P00491 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9110451 | 0.98 | LPAR1 (0.64) | LPAR1LPAR3PGK1PGK2FDPS | |
| SCHEMBL1533943 | 0.77 | LPAR1 (0.96) | LPAR1LPAR3FDPSGGPS1 | |
| SCHEMBL8743575 | 0.76 | LPAR1 (0.59) | LPAR1LPAR3PGK1PGK2FDPS | |
| SCHEMBL193245 | 0.76 | LPAR1 (1.00) | LPAR1LPAR3FDPSGGPS1 | |
| SCHEMBL6666195 | 0.74 | FDPS (0.61) | FDPSGGPS1 | |
| SCHEMBL1533877 | 0.74 | LPAR1 (0.83) | LPAR1LPAR3FDPSGGPS1 | |
| SCHEMBL6154740 | 0.74 | LPAR1 (0.57) | LPAR1LPAR3PGK1PGK2FDPS | |
| SCHEMBL6666067 | 0.73 | FDPS (0.63) | LPAR1LPAR3FDPSGGPS1 | |
| SCHEMBL9514697 | 0.72 | LPAR1 (0.46) | LPAR1LPAR3FDPSGGPS1 | |
| SCHEMBL10277657 | 0.72 | LPAR1 (0.41) | LPAR1LPAR3PGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459216-A2 | IMMUNOGENIC COMPOSITIONS INCLUDING TLR ACTIVITY MODULATORS | Novartis AG (CH) | 2012-06-06 | — | — | EP | disclosed |