Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.40 |
| ▸ | PNLIP | P16233 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8743787 | 0.99 | KMT2A (0.41) | KMT2AMEN1SCN9ATBXA2RPNLIP | |
| SCHEMBL8068683 | 0.93 | SMN1; SMN2 (0.41) | F10HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8059609 | 0.92 | SMN1; SMN2 (0.40) | F10HTTSMN1; SMN2 | |
| SCHEMBL8743801 | 0.90 | PARP10 (0.40) | F10HTTSMN1; SMN2 | |
| SCHEMBL8379266 | 0.90 | HPGD (0.41) | KMT2AF10ALDH1A1HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8816980 | 0.89 | P2RX4 (0.43) | KMT2AMEN1PNLIPF2F10 | |
| SCHEMBL8743793 | 0.89 | MRGPRX1 (0.44) | TBXA2RF2F10SMN1; SMN2BRAF | |
| Hydrochloric Acid SCHEMBL8743791 | 0.89 | PARP10 (0.40) | F10 | |
| Hydrochloric Acid SCHEMBL8374986 | 0.89 | HPGD (0.40) | KMT2AMEN1F10ALDH1A1HTT | |
| SCHEMBL8499411 | 0.88 | GCK (0.42) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589336-B1 | Benzoylguanidines, process for their preparation and their use as antiarrhythmic agents | HOECHST AG (DE) | 1997-01-08 | — | — | EP | claimed |