SCHEMBL8744157

SCHEMBL8744157

FC(F)(F)C(F)(F)C(F)(F)C(C(F)(F)F)(C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
THRB P10828 1/20 0.33
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9539402 0.96 LMNA (0.39) LMNATHRB
SCHEMBL9536133 0.91 LMNA (0.41) LMNATHRBCA2
SCHEMBL9538283 0.87 LMNA (0.47) LMNATHRBCA2
SCHEMBL38665316 0.87 LMNA (0.47) LMNATHRBCA2
SCHEMBL9537525 0.86 LMNA (0.35) LMNA
Perflubutane SCHEMBL9051673 0.80 LMNA (0.54) LMNATHRBCA2
Perflubutane SCHEMBL111514 0.80 LMNA (0.54) LMNATHRBCA2
SCHEMBL1271660 0.76 LMNA (0.35) LMNA
Perflubutane SCHEMBL6229729 0.75 LMNA (0.50) LMNATHRBCA2
SCHEMBL984715 0.75 LMNA (0.61) LMNATHRBCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0753085-A1 PROCESS FOR PREPARING BRANCHED PERFLUOROCHEMICALS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-01-15 EP disclosed
WO-1995026429-A1 PROCESS FOR PREPARING BRANCHED PERFLUOROCHEMICALS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-10-05 WO disclosed
US-5427656-A Process for preparing branched perfluorochemicals MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-06-27 US disclosed