Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.32 |
| ▸ | LSS | P48449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8744202 | 0.94 | TSHR (0.38) | ZDHHC20TSHR | |
| SCHEMBL8744199 | 0.94 | TSHR (0.38) | ZDHHC20TSHR | |
| SCHEMBL8744153 | 0.86 | TSHR (0.41) | TSHR | |
| SCHEMBL8744149 | 0.86 | TSHR (0.41) | TSHR | |
| SCHEMBL8744116 | 0.83 | HTT (0.46) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL8482915 | 0.81 | THRB (0.50) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL8482916 | 0.81 | THRB (0.50) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL10896260 | 0.77 | MEN1 (0.41) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL8373529 | 0.77 | MEN1 (0.41) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL8744194 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612720-B1 | Process for producing 1,4-dicyano-2-butene | SUMITOMO CHEMICAL CO (JP) | 1997-01-08 | — | — | EP | disclosed |
| US-5463103-A | Reacting butene derivative with hydrogen cyanide in presence of catalyst prepared from cuprous halide, lower alkylamine hydrohalide and Lewis acid or basic acetate, carbonate or bicarbonate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-10-31 | — | — | US | disclosed |
| CN-1104630-A | Process for producing 1,4-dicyano-2-butene | SUMITOMO CHEMICAL CO (JP) | 1995-07-05 | — | — | CN | disclosed |
| EP-0612720-A1 | Process for producing 1,4-dicyano-2-butene | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-08-31 | — | — | EP | disclosed |