SCHEMBL8744196

SCHEMBL8744196

Nc1ccccc1-c1cccc2[nH]nnc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
IDO1 P14902 4/20 0.44
KDM4E B2RXH2 5/20 0.42
GAA P10253 5/20 0.42
NPC1 O15118 4/20 0.42
SMN1; SMN2 Q16637 4/20 0.42
HSD17B10 Q99714 3/20 0.42
RAB9A P51151 3/20 0.42
HPGD P15428 3/20 0.42
NPSR1 Q6W5P4 2/20 0.42
MAPT P10636 2/20 0.42
GLA P06280 1/20 0.42
TDP1 Q9NUW8 2/20 0.38
PPARG P37231 1/20 0.38
NCOA2 Q15596 1/20 0.38
NCOA1 Q15788 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
ADORA3 P0DMS8 1/20 0.37
METAP2 P50579 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28763373 0.98 ALDH1A1 (0.46) ALDH1A1L3MBTL1IDO1KDM4EGAA
SCHEMBL29663433 0.98 ALDH1A1 (0.46) ALDH1A1L3MBTL1IDO1KDM4EGAA
SCHEMBL30556736 0.88 METAP2 (0.38) ALDH1A1L3MBTL1IDO1KDM4ENPC1
SCHEMBL31619990 0.88 METAP2 (0.38) ALDH1A1L3MBTL1IDO1KDM4ENPC1
SCHEMBL30884815 0.86 GAA (0.42) ALDH1A1L3MBTL1IDO1KDM4EGAA
SCHEMBL922887 0.86 GAA (0.42) ALDH1A1L3MBTL1IDO1KDM4EGAA
Hydrochloric Acid SCHEMBL6118561 0.84 TDP1 (0.44) ALDH1A1L3MBTL1IDO1KDM4EGAA
SCHEMBL10864543 0.84 GAA (0.41) ALDH1A1L3MBTL1IDO1KDM4EGAA
Formaldehyde SCHEMBL28686038 0.81 TDP1 (0.39) ALDH1A1L3MBTL1IDO1KDM4EGAA
SCHEMBL83054 0.80 MGAM (0.43) ALDH1A1IDO1GAAHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101489525-B Use of aminophenylbenzotriazole derivatives for protecting human and animal skin and hair from the harmful effects of UV radiation and cosmetic compositions thereof CIBA HOLDING INC 2013-06-19 CN disclosed
CN-101489525-A Use of aminophenylbenzotriazole derivatives for protecting human and animal skin and hair from the harmful effects of UV radiation and cosmetic compositions thereof CIBA HOLDING INC (CH) 2009-07-22 CN disclosed
EP-0630954-B1 Low-molecular-weight and polymeric liquid cristalline benztriazoles and their use BASF AG (DE) 1997-01-08 EP disclosed
US-5429770-A Photoconductors, electrography, fluorescent dyes BASF AKTIENGESELLSCHAFT (DE) 1995-07-04 US disclosed
EP-0630954-A1 Low-molecular-weight and polymeric liquid cristalline benztriazoles and their use BASF Aktiengesellschaft (DE) 1994-12-28 EP disclosed
EP-0279091-B1 PHENOLPHTHALEIN POLYARYLATE POLYMERS AND ALLOY COMPOSITIONS THEREOF CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1992-05-27 EP disclosed
EP-0242465-B1 ANTHRACENE POLYARYLATE COPOLYMERS AND ALLOY COMPOSITIONS THEREOF CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1991-11-21 EP disclosed
EP-0258504-B1 FLUORENE POLYARYLATE POLYMERS AND ALLOY COMPOSITIONS THEREOF CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1991-11-06 EP disclosed
EP-0279091-A1 Phenolphthalein polyarylate polymers and alloy compositions thereof CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1988-08-24 EP disclosed
EP-0258504-A1 Fluorene polyarylate polymers and alloy compositions thereof CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1988-03-09 EP disclosed
EP-0242465-A1 Anthracene polyarylate copolymers and alloy compositions thereof CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1987-10-28 EP disclosed
US-4652608-A Alkyl substituted phenolphthalein polyarylate polymer and alloy CHEVRON RESEARCH COMPANY (US) 1987-03-24 US disclosed
US-4612350-A Bis(hydroxyphenyl)fluorene polyarylate polymers and alloys CHEVRON RESEARCH COMPANY (US) 1986-09-16 US disclosed
US-4584335-A 5-keto-bis(hydroxyphenyl)anthracene polyarylate copolymers and alloys CHEVRON RESEARCH COMPANY (US) 1986-04-22 US disclosed
US-4064196-A BLEND OF COPOLYESTERS OF TEREPHTHALIC AND ISOPHTHALIC ACIDS WITH (1)BISPHENOL A AND (2)TETRACHLORO- OR TETRABROMO-BISPHENOL A UNITIKA LTD. (JA) 1977-12-20 US disclosed
US-3946091-A POLYETHYLENE TEREPHTHALATE UNITIKA LIMITED (JA) 1976-03-23 US disclosed