Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8744188 | 0.90 | LMNA (0.41) | ALDH1A1LMNAMAPTMAPK1TSHR | |
| SCHEMBL8744242 | 0.86 | ALDH1A1 (0.30) | ALDH1A1TSHR | |
| SCHEMBL8744171 | 0.79 | TSHR (0.33) | TSHR | |
| SCHEMBL5690286 | 0.77 | LMNA (0.46) | ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL1171644 | 0.75 | LMNA (0.44) | ALDH1A1LMNAMAPTMAPK1TSHR | |
| SCHEMBL5592427 | 0.75 | LMNA (0.44) | ALDH1A1LMNAMAPTMAPK1TSHR | |
| SCHEMBL17748850 | 0.72 | ALDH1A1 (0.35) | ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL9833994 | 0.71 | MAPT (0.39) | ALDH1A1LMNAMAPTMAPK1TSHR | |
| SCHEMBL18894518 | 0.71 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTMAPK1TSHR | |
| SCHEMBL2195297 | 0.71 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612720-B1 | Process for producing 1,4-dicyano-2-butene | SUMITOMO CHEMICAL CO (JP) | 1997-01-08 | — | — | EP | disclosed |
| US-5463103-A | Reacting butene derivative with hydrogen cyanide in presence of catalyst prepared from cuprous halide, lower alkylamine hydrohalide and Lewis acid or basic acetate, carbonate or bicarbonate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-10-31 | — | — | US | disclosed |
| EP-0612720-A1 | Process for producing 1,4-dicyano-2-butene | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-08-31 | — | — | EP | disclosed |