SCHEMBL8744280

SCHEMBL8744280

CCC(CC)(CC)CCCN

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 9/20 0.38
TSHR P16473 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
ALDH1A1 P00352 1/20 0.38
EPHX1 P07099 1/20 0.38
NFKB1 P19838 1/20 0.35
KIF11 P52732 1/20 0.34
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA3 P07451 2/20 0.33
CA4 P22748 2/20 0.33
CA6 P23280 2/20 0.33
CA5A P35218 2/20 0.33
CA7 P43166 2/20 0.33
CA9 Q16790 2/20 0.33
CA14 Q9ULX7 2/20 0.33
CA5B Q9Y2D0 2/20 0.33
FDPS P14324 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9169385 0.91 DNM1 (0.43) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL14812906 0.88 DNM1 (0.35) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL14812442 0.88 DNM1 (0.35) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL29480607 0.88 DNM1 (0.48) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL3281516 0.88 DNM1 (0.48) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL1115495 0.88 DNM1 (0.48) DNM1TSHRMEN1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL10933147 0.86 DNM1 (0.50) DNM1TSHRMEN1KMT2AALDH1A1
Bromide SCHEMBL9736748 0.86 DNM1 (0.50) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL15335412 0.86 DNM1 (0.46) DNM1TSHRMEN1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL11240602 0.86 DNM1 (0.50) DNM1TSHRMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0427587-B1 Process for the preparation of AZT (3'-azido-3'-deoxy-thymidine) and related compounds UNIV PARIS CURIE (FR) 1997-01-15 EP claimed
US-5124442-A PROCESS FOR PREPARING AZT (3'-AZIDO-3'-DEOXY-THYMIDINE) AND RELATED COMPOUNDS UNIVERSITE PIERRE ET MARIE CURIE (PARIS VI) (FR) 1992-06-23 US claimed
EP-0427587-A1 Process for the preparation of AZT (3'-azido-3'-deoxy-thymidine) and related compounds UNIVERSITE PIERRE ET MARIE CURIE PARIS VI (FR) 1991-05-15 EP claimed
CN-120059143-A Semi-continuous production method of activity-controllable polyester 万华化学集团股份有限公司 2025-05-30 CN disclosed
WO-2021055627-A1 SUBSTITUTED N-HETEROCYCLIC CARBOXAMIDES AS ACID CERAMIDASE INHIBITORS AND THEIR USE AS MEDICAMENTS BIAL- BIOTECH INVESTMENTS, INC. (US) 2021-03-25 WO disclosed
EP-0332178-B1 2-CYCLOPENTENONE DERIVATIVES TEIJIN LIMITED (JP) 1993-06-16 EP disclosed
US-5149711-A Antitumor agents TEIJIN LIMITED (JP) 1992-09-22 US disclosed
EP-0180399-B1 ANTI-TUMOR 4-HYDROXY-2-CYCLOPENTENONES TEIJIN LIMITED (JP) 1992-05-20 EP disclosed
EP-0332178-A1 2-cyclopentenone derivatives TEIJIN LIMITED (JP) 1989-09-13 EP disclosed
US-4711895-A 4-hydroxy-2-cyclopentenone, process for production thereof, pharmaceutical composition comprising it TEIJIN LIMITED (JP) 1987-12-08 US disclosed
EP-0180399-A2 Anti-tumor 4-Hydroxy-2-cyclopentenones TEIJIN LIMITED (JP) 1986-05-07 EP disclosed