Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | UBE2M | P61081 | 8/20 | 0.49 |
| ▸ | DCUN1D1 | Q96GG9 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.47 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8744403 | 0.80 | GNAO1 (0.50) | KCNH2 | |
| SCHEMBL8744425 | 0.79 | KCNH2 (0.53) | KCNH2UBE2MDCUN1D1RIPK1CYP2J2 | |
| SCHEMBL8744476 | 0.79 | KCNH2 (0.55) | KCNH2UBE2MDCUN1D1KMT2AKDM4E | |
| SCHEMBL8744343 | 0.76 | BCHE (0.50) | KCNH2 | |
| SCHEMBL8872700 | 0.76 | GNAO1 (0.54) | KCNH2 | |
| SCHEMBL5199917 | 0.73 | ACHE (0.56) | KCNH2KMT2AMEN1OPRM1 | |
| SCHEMBL8744456 | 0.72 | GNAO1 (0.57) | KCNH2 | |
| Hydrochloric Acid SCHEMBL6491944 | 0.72 | ACHE (0.55) | KCNH2KMT2AMEN1OPRM1 | |
| SCHEMBL8744379 | 0.70 | GNAO1 (0.50) | KCNH2 | |
| SCHEMBL8744375 | 0.69 | BCHE (0.44) | KCNH2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614534-A | Derivatives of β, β-dimethyl-4-piperidineethanamine as inhibitors of the cholesterol biosynthesis | FOURNIER INDUSTRIE ET SANTE (FR) | 1997-03-25 | — | — | US | disclosed |
| EP-0699187-B1 | BETA,BETA-DIMETHYL-4-PIPERIDINEETHANAMINE DERIVATIVES AS INHIBITORS OF THE CHOLESTEROL BIOSYNTHESIS | FOURNIER IND & SANTE (FR) | 1997-01-22 | — | — | EP | disclosed |
| EP-0699187-A1 | DERIVATIVES OF -g(b), -g(b)-DIMETHYL-4-PIPERIDINEETHANAMINE AS INHIBITORS OF THE CHOLESTEROL BIOSYNTHESIS | FOURNIER IND & SANTE (FR) | 1996-03-06 | — | — | EP | disclosed |
| WO-1994026713-A1 | DERIVATIVES OF β, β-DIMETHYL-4-PIPERIDINEETHANAMINE AS INHIBITORS OF THE CHOLESTEROL BIOSYNTHESIS | FOURNIER INDUSTRIE ET SANTE (FR) | 1994-11-24 | — | — | WO | disclosed |