Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.81 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.81 |
| ▸ | DPP4 | P27487 | 1/20 | 0.81 |
| ▸ | MEN1 | O00255 | 1/20 | 0.81 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.81 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.81 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.81 |
| ▸ | GAPDH | P04406 | 1/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.81 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.81 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.81 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.81 |
| ▸ | STAT6 | P42226 | 1/20 | 0.81 |
| ▸ | PI4KA | P42356 | 1/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.81 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.81 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.81 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.81 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL836051 | 1.00 | DOT1L (0.81) | DOT1LADORA3DPP4MEN1SLC28A1 | |
| SCHEMBL8332213 | 1.00 | DOT1L (0.81) | DOT1LADORA3DPP4MEN1SLC28A1 | |
| SCHEMBL506314 | 1.00 | DOT1L (0.81) | DOT1LADORA3DPP4MEN1SLC28A1 | |
| SCHEMBL506313 | 1.00 | DOT1L (0.81) | DOT1LADORA3DPP4MEN1SLC28A1 | |
| Phosphoric Acid SCHEMBL1972743 | 0.94 | P2RY1 (0.75) | DOT1LADORA3DPP4MEN1SLC28A1 | |
| Adenosine SCHEMBL6674206 | 0.91 | ADORA3 (0.97) | DOT1LADORA3DPP4MEN1SLC28A1 | |
| SCHEMBL13834962 | 0.90 | ADORA3 (0.82) | DOT1LADORA3DPP4MEN1SLC28A1 | |
| SCHEMBL28668199 | 0.90 | DOT1L (0.78) | DOT1LADORA3DPP4MEN1SLC28A1 | |
| SCHEMBL13834960 | 0.90 | ADORA3 (0.82) | DOT1LADORA3DPP4MEN1SLC28A1 | |
| SCHEMBL13834964 | 0.90 | ADORA3 (0.82) | DOT1LADORA3DPP4MEN1SLC28A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113813280-B | Sugar ring modified compound, preparation method and application thereof in preparation of products with anti-fatigue function | 中国人民解放军军事科学院军事医学研究院 | 2023-07-07 | — | — | CN | disclosed |
| CN-113813280-A | Sugar ring modified nucleoside analogue, preparation method and application thereof in preparation of product with anti-fatigue function | 中国人民解放军军事科学院军事医学研究院 | 2021-12-21 | — | — | CN | disclosed |
| WO-2018075947-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-04-26 | — | — | WO | disclosed |
| EP-2471804-A1 | Diadenosine antibacterial compounds | Institut Pasteur (FR) | 2012-07-04 | — | — | EP | disclosed |
| WO-2012040318-A2 | COMPOSITIONS, METHODS AND KITS FOR DETECTING MELANOMA AND MARGINS OF MELANOMA | UNIVERSITY OF MIAMI (US) | 2012-03-29 | — | — | WO | disclosed |
| WO-2012014898-A1 | LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT | 日産化学工業株式会社 (JP) | 2012-02-02 | — | — | WO | disclosed |
| US-6534651-B2 | Substituted isoindolinone derivatives | INOTEK PHARMACEUTICALS CORP. | 2003-03-18 | — | — | US | disclosed |
| US-6534651-B2 | Substituted isoindolinone derivatives | INOTEK PHARMACEUTICALS CORP. | 2003-03-18 | — | — | US | disclosed |