Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1424113 | 0.83 | NCF1 (0.52) | NCF1 | |
| SCHEMBL22930835 | 0.82 | HRH3 (0.32) | NCF1 | |
| SCHEMBL3668347 | 0.81 | NCF1 (0.36) | NCF1 | |
| SCHEMBL5901179 | 0.80 | BRD4 (0.35) | NCF1 | |
| SCHEMBL16838116 | 0.78 | AKR1C3 (0.32) | — | |
| SCHEMBL17545539 | 0.78 | CYP1A2 (0.42) | — | |
| SCHEMBL16120530 | 0.77 | NCF1 (0.33) | NCF1 | |
| SCHEMBL6274327 | 0.75 | NCF1 (0.32) | NCF1 | |
| SCHEMBL6628398 | 0.75 | EPHX2 (0.33) | NCF1 | |
| SCHEMBL17540119 | 0.74 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614534-A | Derivatives of β, β-dimethyl-4-piperidineethanamine as inhibitors of the cholesterol biosynthesis | FOURNIER INDUSTRIE ET SANTE (FR) | 1997-03-25 | — | — | US | disclosed |
| EP-0699187-B1 | BETA,BETA-DIMETHYL-4-PIPERIDINEETHANAMINE DERIVATIVES AS INHIBITORS OF THE CHOLESTEROL BIOSYNTHESIS | FOURNIER IND & SANTE (FR) | 1997-01-22 | — | — | EP | disclosed |
| EP-0699187-A1 | DERIVATIVES OF -g(b), -g(b)-DIMETHYL-4-PIPERIDINEETHANAMINE AS INHIBITORS OF THE CHOLESTEROL BIOSYNTHESIS | FOURNIER IND & SANTE (FR) | 1996-03-06 | — | — | EP | disclosed |