SCHEMBL8744491

SCHEMBL8744491

CC(C)OC1=CC(=O)c2ccccc2C1=O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 5/20 0.67
CDC25A P30304 4/20 0.67
IDO1 P14902 2/20 0.67
GAPDH P04406 1/20 0.58
CYP1A2 P05177 3/20 0.52
CYP2C9 P11712 3/20 0.52
CYP2C19 P33261 3/20 0.52
ALDH1A1 P00352 3/20 0.52
LMNA P02545 3/20 0.52
MAPT P10636 3/20 0.52
HPGD P15428 3/20 0.52
MAOA P21397 2/20 0.52
MAOB P27338 2/20 0.52
MEN1 O00255 2/20 0.52
GAA P10253 2/20 0.52
MAPK1 P28482 2/20 0.52
KMT2A Q03164 2/20 0.52
ATM Q13315 2/20 0.52
TP53 P04637 2/20 0.52
CYP3A4 P08684 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5595975 0.85 PTPN1 (0.67) CDC25BCDC25AIDO1ALDH1A1MAPT
SCHEMBL10706935 0.84 GAPDH (0.60) CDC25BCDC25AIDO1GAPDHCYP1A2
SCHEMBL9627371 0.82 CDC25B (0.59) CDC25BCDC25AIDO1GAPDHCYP1A2
SCHEMBL10899554 0.81 CDC25B (0.62) CDC25BCDC25AIDO1GAPDHCYP1A2
SCHEMBL6052851 0.81 CDC25B (0.57) CDC25BCDC25AIDO1GAPDHCYP1A2
2-Methoxy-1,4-Naphthoquinone SCHEMBL571061 0.80 CDC25B (1.00) CDC25BCDC25AIDO1GAPDHCYP1A2
2-Methoxy-1,4-Naphthoquinone SCHEMBL29401525 0.80 CDC25B (1.00) CDC25BCDC25AIDO1GAPDHCYP1A2
SCHEMBL9629381 0.80 CDC25B (0.56) CDC25BCDC25AIDO1GAPDHCYP1A2
SCHEMBL9714028 0.79 CDC25B (0.42) CDC25BCDC25AIDO1GAPDHCYP1A2
SCHEMBL29209333 0.79 CDC25B (0.58) CDC25BCDC25AIDO1GAPDHCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4451556-A Tellurium imaging composition including base ENERGY CONVERSION DEVICES, INC. (US) 1984-05-29 US claimed
EP-0098018-A2 Imaging film and composition employing an organo-metallic compound and method for recording electromagnetic radiation ENERGY CONVERSION DEVICES, INC. (US) 1984-01-11 EP claimed
US-4340662-A PHOTOSENSITIVE FILMS ENERGY CONVERSION DEVICES, INC. (US) 1982-07-20 US claimed
US-4324852-A REDOX COUPLES EASTMAN KODAK COMPANY (US) 1982-04-13 US claimed
US-4281058-A A PHOTOSENSITIVE COMPLEX OF THE TELLURIUM COMPOUND AND A GLYCEROL ETHER OR THIOETHER; NONSILVER PHOTOGRAPHY ENERGY CONVERSION DEVICES, INC. (US) 1981-07-28 US claimed
US-4201588-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, CARBAZIDES OR QUINONES AS PHOTOREDUCTANT; EXTERNAL HYDROGEN SOURCE EASTMAN KODAK COMPANY (US) 1980-05-06 US claimed
US-4195998-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, QUINONE OR CARBAZIDE PHOTOREDUCTANT EASTMAN KODAK COMPANY (US) 1980-04-01 US claimed
US-5698363-A IMAGEWISE PROVIDING IN SECOND LAYER COMPONENT NOT IN FIRST LAYER, SELECTED FROM COBALT COMPLEX HAVING AMMONIA OR PRIMARY AMINE LIGAND, COMPOUND HAVING ABSORPTION WAVELENGTH CHANGED BY LIGAND, COMPOUND CAUSING LIGAND TO BE RELEASED KONICA CORPORATION (JP) 1997-12-16 US disclosed
EP-0753415-A2 Image forming method KONICA CORPORATION (JP) 1997-01-15 EP disclosed
US-5476755-A Exposing to light for development, heating for fixing and acid treatment; photoreduction of cobalt complex KONICA CORPORATION (JP) 1995-12-19 US disclosed
EP-0327318-B1 Heat-sensitive recording materials FUJI PHOTO FILM CO LTD (JP) 1995-07-19 EP disclosed
US-5415984-A A support with a cobalt complex for images KONICA CORPORATION (JP) 1995-05-16 US disclosed
US-5091558-A Topical administeration SYNTEX (U.S.A.) INC. (US) 1992-02-25 US disclosed
US-4195998-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, QUINONE OR CARBAZIDE PHOTOREDUCTANT EASTMAN KODAK COMPANY (US) 1980-04-01 US disclosed
US-4196002-A HEXAARYLBISMIIDAZOLE, COLORLESS EASTMAN KODAK COMPANY (US) 1980-04-01 US disclosed
US-4188218-A Images formed by decomposition of Te (II) coordination complexes EASTMAN KODAK COMPANY (US) 1980-02-12 US disclosed
US-4171221-A NONSILVER PHOTOGTAPHY EASTMAN KODAK COMPANY (US) 1979-10-16 US disclosed
EP-0002546-A2 Improved photosensitive recording material and a method of recording information by exposure of said material to information-wise modulated activating ultra-violet and/or visible light AGFA-GEVAERT N.V. (BE) 1979-06-27 EP disclosed
US-4124392-A LEUCO DYES EASTMAN KODAK COMPANY (US) 1978-11-07 US disclosed
US-4107155-A Polysulfonamides EASTMAN KODAK COMPANY (US) 1978-08-15 US disclosed