SCHEMBL8744584

SCHEMBL8744584

CCCCCCCCCCCCCCCCCC(=O)Nc1c[c]cc(NC(=O)CCCCCCCCCCCCCCCCC)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.54
NPC1 O15118 1/20 0.54
RAB9A P51151 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
POLB P06746 1/20 0.52
SOAT2 O75908 1/20 0.52
SOAT1 P35610 1/20 0.52
ENPP2 Q13822 1/20 0.51
DGAT2 Q96PD7 1/20 0.51
PSMB11 A5LHX3 1/20 0.51
PSMA7 O14818 1/20 0.51
PSMB1 P20618 1/20 0.51
PSMA1 P25786 1/20 0.51
PSMA2 P25787 1/20 0.51
PSMA3 P25788 1/20 0.51
PSMA4 P25789 1/20 0.51
PSMB8 P28062 1/20 0.51
PSMB9 P28065 1/20 0.51
PSMA5 P28066 1/20 0.51
PSMB4 P28070 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16118213 0.88 LMNA (0.61) LMNANPC1RAB9ASMN1; SMN2POLB
SCHEMBL27975953 0.86 LMNA (0.63) LMNANPC1RAB9ASMN1; SMN2POLB
SCHEMBL6152735 0.81 LMNA (0.58) LMNANPC1RAB9ASMN1; SMN2POLB
SCHEMBL6537046 0.81 LMNA (0.58) LMNANPC1RAB9ASMN1; SMN2POLB
SCHEMBL11715260 0.81 LMNA (0.58) LMNANPC1RAB9ASMN1; SMN2POLB
SCHEMBL8356323 0.81 LMNA (0.58) LMNANPC1RAB9ASMN1; SMN2POLB
SCHEMBL9095488 0.81 LMNA (0.58) LMNANPC1RAB9ASMN1; SMN2POLB
SCHEMBL9739986 0.81 LMNA (0.58) LMNANPC1RAB9ASMN1; SMN2POLB
SCHEMBL9858666 0.80 ENPP2 (0.71) LMNANPC1RAB9ASMN1; SMN2POLB
SCHEMBL675018 0.80 ENPP2 (0.71) LMNANPC1RAB9ASMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0537659-B1 Silver halide color photographic light-sensitive material, and method of processing the same FUJI PHOTO FILM CO LTD (JP) 1997-01-15 EP disclosed
EP-0537659-A1 Silver halide color photographic light-sensitive material, and method of processing the same FUJI PHOTO FILM CO., LTD. (JP) 1993-04-21 EP disclosed