SCHEMBL8744607

SCHEMBL8744607

CN1C=NC(S)N1c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ GSK3A P49840 1/20 0.31
▸ GSK3B P49841 1/20 0.31
▸ NOTUM Q6P988 1/20 0.31
▸ HPGDS O60760 1/20 0.30
▸ ALKBH2 Q6NS38 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4296963 0.70 NPC1 (0.33) —
SCHEMBL3150312 0.70 KMT2A (0.38) —
SCHEMBL3133853 0.64 NPC1 (0.36) NOTUM
SCHEMBL3840285 0.62 HTR1A (0.38) GSK3AGSK3B
SCHEMBL5155507 0.60 SMN1; SMN2 (0.33) GSK3AGSK3B
SCHEMBL1780687 0.59 SMN1; SMN2 (0.33) GSK3AGSK3B
SCHEMBL13283382 0.58 RECQL (0.40) GSK3AGSK3B
SCHEMBL9293106 0.58 GAA (0.33) —
SCHEMBL18365312 0.57 MAPK1 (0.37) —
SCHEMBL22200061 0.57 LOX (0.35) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0534283-B1 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1997-12-17 — — EP disclosed
EP-0537659-B1 Silver halide color photographic light-sensitive material, and method of processing the same FUJI PHOTO FILM CO LTD (JP) 1997-01-15 — — EP disclosed
US-5437968-A Having improved push-processing suitability; emulsion layers containing yellow colloidal silver; development inhibitor component FUJI PHOTO FILM CO., LTD. (JP) 1995-08-01 — — US disclosed
US-5290676-A Methine dye sensitizers, controlling size and shape of silver halide grains FUJI PHOTO FILM CO., LTD. (JP) 1994-03-01 — — US disclosed
EP-0537659-A1 Silver halide color photographic light-sensitive material, and method of processing the same FUJI PHOTO FILM CO., LTD. (JP) 1993-04-21 — — EP disclosed
EP-0534283-A2 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1993-03-31 — — EP disclosed
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