Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8744673 | 0.81 | TSHR (0.39) | TSHRALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL28029632 | 0.80 | TSHR (0.38) | TSHRALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL1787940 | 0.77 | KMT2A (0.36) | TSHRALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL1787216 | 0.77 | TSHR (0.36) | TSHRALDH1A1SMN1; SMN2ADAM17LMNA | |
| SCHEMBL9363325 | 0.76 | POLB (0.39) | TSHRALDH1A1SMN1; SMN2LMNAPTGS1 | |
| SCHEMBL2034156 | 0.75 | TRPA1 (0.36) | TSHRALDH1A1SMN1; SMN2HTTCCR5 | |
| SCHEMBL5350084 | 0.72 | MAOB (0.40) | TSHRALDH1A1SMN1; SMN2LMNACCR5 | |
| SCHEMBL1783397 | 0.72 | TSHR (0.44) | TSHRALDH1A1LMNAPTGS1PTGS2 | |
| SCHEMBL1785146 | 0.72 | MAOB (0.42) | TSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL17589775 | 0.71 | MAOB (0.36) | TSHRALDH1A1SMN1; SMN2HTTCCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258404-A | 3-(Unsubstituted or substituted benzyl)-1-alkyl-2-oxocyclopentane carboxylic acid alkyl ester derivatives, method for preparation fungicides, and use thereof as intermediate compounds | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-11-02 | — | — | US | claimed |
| EP-0537909-B1 | 3-(Unsubstituted or substituted benzyl)-1-alkyl-2-oxocyclopentane carboxylic acid alkyl ester derivatives, and their preparation and use | KUREHA CHEMICAL IND CO LTD (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-5258404-A | 3-(Unsubstituted or substituted benzyl)-1-alkyl-2-oxocyclopentane carboxylic acid alkyl ester derivatives, method for preparation fungicides, and use thereof as intermediate compounds | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-11-02 | — | — | US | disclosed |
| EP-0537909-A1 | 3-(Unsubstituted or substituted benzyl)-1-alkyl-2-oxocyclopentane carboxylic acid alkyl ester derivatives, and their preparation and use | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-04-21 | — | — | EP | disclosed |