SCHEMBL8744698

SCHEMBL8744698

Cc1cccc(C(=O)CN)c1C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45
MYC P01106 1/20 0.43
HSD17B10 Q99714 3/20 0.42
ALDH1A1 P00352 3/20 0.42
KDM4E B2RXH2 1/20 0.42
HPGD P15428 1/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
TRPA1 O75762 2/20 0.42
LMNA P02545 2/20 0.42
CYP3A4 P08684 2/20 0.42
AKR1B10 O60218 1/20 0.42
ABCB11 O95342 1/20 0.42
DHFR P00374 1/20 0.42
MPO P05164 1/20 0.42
CYP1A2 P05177 1/20 0.42
CHRM1 P11229 1/20 0.42
CYP2C9 P11712 1/20 0.42
AKR1B1 P15121 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3136082 0.83 ERCC5 (0.58) MYCHPGDMEN1KMT2AERCC5
SCHEMBL11599056 0.82 ERCC5 (0.49) ESR1ESR2HSD17B10ALDH1A1KDM4E
SCHEMBL581465 0.82 ESR1 (0.46) ESR1ESR2MYCHSD17B10ALDH1A1
SCHEMBL10770139 0.82 ESR1 (0.46) ESR1ESR2MYCHSD17B10ALDH1A1
SCHEMBL30578286 0.82 ESR1 (0.46) ESR1ESR2MYCHSD17B10ALDH1A1
Hydrochloric Acid SCHEMBL6110153 0.82 ERCC5 (0.56) MYCHPGDMEN1KMT2AERCC5
SCHEMBL28391695 0.80 ESR1 (0.45) ESR1ESR2MYCHSD17B10ALDH1A1
SCHEMBL6314438 0.79 TRPA1 (0.43) ESR1ESR2MYCHSD17B10ALDH1A1
SCHEMBL5309095 0.78 CTNNB1 (0.46) ESR1ESR2HSD17B10ALDH1A1HPGD
SCHEMBL25230164 0.77 GAA (0.47) ESR1ESR2HSD17B10ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117940478-A Phenol resin, epoxy resin, curable resin composition, cured product, fiber-reinforced composite material, and fiber-reinforced resin molded article DIC株式会社 2024-04-26 CN disclosed
CN-106810763-A A kind of gear shift lever of auto vehicles base material and preparation method thereof 芜湖天鸿汽车零部件有限公司 2017-06-09 CN disclosed
EP-0653421-B1 Process for preparing 2-cyanoimidazole compounds ISHIHARA SANGYO KAISHA (JP) 1997-01-15 EP disclosed
US-5552557-A Process for preparing 2-cyanoimidazole compounds by reaction of an amino ketone compound ISHIHARA SANGYO KAISHA, LTD. (JP) 1996-09-03 US disclosed
EP-0653421-A1 Process for preparing 2-cyanoimidazole compounds ISHIHARA SANGYO KAISHA LTD. (JP) 1995-05-17 EP disclosed