Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.35 |
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GAPDH | P04406 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10913542 | 0.72 | MAPT (0.44) | LMNAKMT2AMEN1POLBTDP1 | |
| SCHEMBL10843417 | 0.70 | SMN1; SMN2 (0.44) | PBRM1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8648444 | 0.70 | PBRM1 (0.32) | PBRM1KMT2AMEN1GAPDHPOLB | |
| SCHEMBL8744823 | 0.70 | TAS1R3 (0.32) | PBRM1KMT2AMEN1GAPDHPOLB | |
| SCHEMBL10541313 | 0.70 | TNKS2 (0.46) | USP2LMNAADORA3OTUD7BKMT2A | |
| SCHEMBL11224128 | 0.69 | KDM1A (0.32) | KMT2AL3MBTL1MAPTALDH1A1HSD17B10 | |
| SCHEMBL1895535 | 0.68 | MAPT (0.48) | USP2LMNAADORA3KMT2ATDP1 | |
| SCHEMBL15669931 | 0.68 | MAPT (0.48) | USP2LMNAADORA3KMT2ATDP1 | |
| SCHEMBL1894049 | 0.68 | MAPT (0.48) | USP2LMNAADORA3KMT2ATDP1 | |
| SCHEMBL12687865 | 0.67 | MEN1 (0.32) | KMT2AMEN1GAPDHPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456063-B1 | 1-H-3-aryl-pyrrolidin-2,4-dion-derivatives | BAYER AG (DE) | 1997-01-22 | — | — | EP | disclosed |
| US-5258527-A | Insecticidal, acaricidal and herbicidal 1-H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-02 | — | — | US | disclosed |
| EP-0456063-A2 | 1-H-3-aryl-pyrrolidin-2,4-dion-derivatives | BAYER AG (DE) | 1991-11-13 | — | — | EP | disclosed |